DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx6 and snx5

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001016081.1	Gene:	snx5 / 548835	XenbaseID:	XB-GENE-947018	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	409	Identity:	202/409 - (49%)
Similarity:	280/409 - (68%)	Gaps:	19/409 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 APSGATNGSGS--ATSPDSSSSAPATPAVLGENALHVEISDALSEKEKVKFTVHTRTTLPGFSKK 104
            ||....:||..  :.|.|.:|          :.:|.::|.|||||::||||||||:|.||.|...
Frog     3 APGIEESGSSKLRSVSVDLNS----------DPSLQIDIPDALSERDKVKFTVHTKTKLPNFKSP 57

  Fly   105 DNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKS 169
            |.:|.|.||:|:||||.:.|.:||||.||||.|.:||||..|||:|:||||||:|||:||.|||.
Frog    58 DFSVTRLHEDFIWLHDSLIETEDYAGLIIPPAPAKPDFDGPREKMQKLGEGEGSMTKDEFSKMKQ 122

  Fly   170 ELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLG 234
            ||||||||.||||||:|||||:|:||||:...|.:..:||||||||..:.:....:||.|.||:.
Frog   123 ELEAEYLAVFKKTVAVHEVFLQRIASHPILCKDTNFHIFLEYDQDLSVRRKNTKEMFGVFFKSMV 187

  Fly   235 KTTDEILLSATVRDVNDFFENELQFLTEYHGHLREAALRTEKMTQRHKDVGDSHQKISNALTQLS 299
            |:.||:|.|. |::|::||:.|..||..|:..::::..:.::||:.||:|.|.:..||.|||.::
Frog   188 KSADEVLFSG-VKEVDEFFDQEKTFLVNYYNRIKDSCAKADRMTRTHKNVADDYIHISAALTCVA 251

  Fly   300 TTEKGNVETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYE 364
            ..|...|..::.|.||:||:::.:|.||||||||||.:.||||..:.:|||.||.||.:.|..::
Frog   252 EEENTQVRKYLLKLAELFEKLRKVEARVASDQDLKLSELLRYYMLNIEAAKDLLHRRTKSLGDFQ 316

  Fly   365 AANRNLEKARSKNKDVHAPLEVQEAETAQAEACEKFESMSACGKEELIGFRNRRVAAFKKSLVEL 429
            .:|:.|:|||.|:||      |:.||..|.|.|:|||.:|...|:||:||..||||||:|:|||:
Frog   317 NSNKALDKARLKSKD------VKPAEQHQHECCQKFEKLSESAKQELVGFNRRRVAAFRKNLVEM 375

  Fly   430 SELEIKHAKTQYEYLRQSL 448
            :||||||||.....|:..:
Frog   376 TELEIKHAKNNVSLLQSCI 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	89/139 (64%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	99/221 (45%)
snx5	NP_001016081.1	PX_SNX5	25..165	CDD:132824	89/139 (64%)
snx5	NP_001016081.1	BAR_SNX5	181..398	CDD:153347	99/221 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	425	1.000	Inparanoid score	I1729
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1009572at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48651
Panther	1	1.100	-	-	LDO	PTHR45850
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1564
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.160