DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and snx18b

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001015063.1	Gene:	snx18b / 548603	ZFINID:	ZDB-GENE-080213-6	Length:	563	Species:	Danio rerio

Alignment Length:	320	Identity:	67/320 - (20%)
Similarity:	111/320 - (34%)	Gaps:	102/320 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 DALSEKEK-VKFTVHTRTTLPGFSKKDNNVVRQH-------EEFVWLH-DRIEENDDYAG--YII 133
            |.:|::.| :.:.::..|:.|..||.|   |.||       :|..|.. .|..|.||..|  :.:
Zfish   290 DFISKRRKGLIWWMNHMTSHPVLSKCD---VFQHFLTCSSTDEKAWKQGKRKAEKDDLVGANFFL 351

  Fly   134 PPCPPRPDFDASREKLQRLGEGEGNMTKE------EFKKMKSELEAEYLATFKKTVAMHEVFLRR 192
            ..|||....|.  ::::...||....||:      :.....:|...:.:..|||...
Zfish   352 TICPPALPLDL--QEVENKVEGFKTFTKKMDENIIQVNVTINEFARKQITGFKKEYQ-------- 406

  Fly   193 LASHPVFRVDQHLKVF---LEYDQDLCAKP-RKKMAIFGGFVKSLGKTTDEILLSATVRDVNDFF 253
                   ||.|..::.   .|.||.:.:.| .|.||..|...:::|                |:|
Zfish   407 -------RVGQAFRLLSQAFEVDQQVFSSPLNKAMANTGEVYETIG----------------DYF 448

  Fly   254 ENE--------LQFLTEYHGHL---------REAALRTEKMTQRH---KD--VGDSHQKISNALT 296
            ..:        ...|..|.|||         ::.||...|.:|:|   ||  .|.......|.::
Zfish   449 AEQPRQDLEPISDLLAIYQGHLANFPDIIHVQKGALTKAKESQKHGEEKDGTAGGGINDRCNIIS 513

  Fly   297 QLSTTE------------KGNVETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQR 344
            ..:..|            |..::.|:.:....|::|..           ||.:.|..|.:
Zfish   514 CATLAEIQHFHCIRVRDFKAQMQYFLQQQISFFQKITG-----------KLEEALDMYDQ 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	34/151 (23%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	26/151 (17%)
snx18b	NP_001015063.1	SH3	4..58	CDD:302595
		PX_domain	219..345	CDD:295365	17/57 (30%)
		BAR_3_WASP_bdg	328..561	CDD:287434	55/276 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910