DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx6 and snx6

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_988999.1	Gene:	snx6 / 394595	XenbaseID:	XB-GENE-943801	Length:	406	Species:	Xenopus tropicalis

Alignment Length:	406	Identity:	216/406 - (53%)
Similarity:	291/406 - (71%)	Gaps:	13/406 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GSATSPDSSSSAPATPAVLG-----ENALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVVR 110
            |....||..|.....|..:.     :..|.|:|||||||::||||||||:::||.|.:.:.:|||
Frog     4 GLDDGPDFLSEEDRAPRAINVDLQPDATLQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVR 68

  Fly   111 QHEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEY 175
            |||||:||||...||::||||||||.||||||||||||||:||||||:||||||.|||.||||||
Frog    69 QHEEFIWLHDSFVENEEYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEY 133

  Fly   176 LATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEI 240
            ||.||||||||||||.|:|:||:.|.|.:..|||||:|||..:.:.|......|.||:.|:.|.:
Frog   134 LAIFKKTVAMHEVFLCRVAAHPILRKDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKSVVKSADGV 198

  Fly   241 LLSATVRDVNDFFENELQFLTEYHGHLREAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGN 305
            ::|.| :||:|||::|..||.|||..:::|:.:::|||:.||:..|.:.:|.:::..|.|.:..:
Frog   199 IVSGT-KDVDDFFDHERTFLVEYHNRVKDASAKSDKMTRSHKNAADDYNRIGSSMYTLGTQDNSD 262

  Fly   306 VETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNL 370
            :..|..:.:|:|::.:.:|.|||:|:||||.|.|:||.|:|.|||.||.||.|.|..||.||:.|
Frog   263 ICKFFLRVSELFDKTRKIEARVAADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKAL 327

  Fly   371 EKARSKNKDVHAPLEVQEAETAQAEACEKFESMSACGKEELIGFRNRRVAAFKKSLVELSELEIK 435
            :|||:|||||.|      |||.|..:|:|||.:|...|:||:.|:.||||||:|:||||:|||:|
Frog   328 DKARAKNKDVLA------AETTQQLSCQKFEKISESAKQELMDFKTRRVAAFRKNLVELAELELK 386

  Fly   436 HAKTQYEYLRQSLLAL 451
            |||...:.| ||.||:
Frog   387 HAKGNLQLL-QSCLAV 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	101/139 (73%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	105/224 (47%)
snx6	NP_988999.1	PX_SNX6	30..170	CDD:132825	101/139 (73%)
snx6	NP_988999.1	BAR	186..403	CDD:325158	105/224 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12304
Inparanoid	1	1.050	425	1.000	Inparanoid score	I1729
OMA	1	1.010	-	-		QHG52498
OrthoDB	1	1.010	-	-		D1009572at2759
OrthoFinder	1	1.000	-	-		FOG0004890
OrthoInspector	1	1.000	-	-		otm48651
Panther	1	1.100	-	-	O	PTHR45850
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3071
SonicParanoid	1	1.000	-	-		X1564
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110