DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and Snx6

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001102181.1	Gene:	Snx6 / 362738	RGDID:	1304647	Length:	406	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	211/379 - (55%)
Similarity:	282/379 - (74%)	Gaps:	7/379 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 ALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCP 137
            ||.|:|||||||::||||||||:::||.|.:.:.:||||||||:||||...||:|||||||||.|
  Rat    31 ALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAP 95

  Fly   138 PRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVD 202
            |||||||||||||:||||||:||||||.|||.||||||||.||||||||||||.|:|:||:.|.|
  Rat    96 PRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRKD 160

  Fly   203 QHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLSATVRDVNDFFENELQFLTEYHGHL 267
            .:..|||||:|||..:.:.|......|.|::.|:.|.:::|. |:||:||||:|..||.|||..:
  Rat   161 LNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSG-VKDVDDFFEHERTFLLEYHNRV 224

  Fly   268 REAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGNVETFVAKTAEIFERIKNLETRVASDQD 332
            ::|:.::::||:.||...|.:.:|.::|..|.|.:..::..|..|.:|:|::.:.:|.||::|:|
  Rat   225 KDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADED 289

  Fly   333 LKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNLEKARSKNKDVHAPLEVQEAETAQAEAC 397
            |||.|.|:||.|:|.|||.||.||.|.|..||.||:.|:|||:||||      |.:|||:|...|
  Rat   290 LKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKD------VLQAETSQQLCC 348

  Fly   398 EKFESMSACGKEELIGFRNRRVAAFKKSLVELSELEIKHAKTQYEYLRQSLLAL 451
            :|||.:|...|:|||.|:.||||||:|:||||:|||:||||...:.|:..|..|
  Rat   349 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVL 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	103/138 (75%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	103/224 (46%)
Snx6	NP_001102181.1	PX_SNX6	30..170	CDD:132825	103/138 (75%)
Snx6	NP_001102181.1	BAR_SNX6	186..403	CDD:153346	100/216 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	220	1.000	Domainoid score	I2532
eggNOG	1	0.900	-	-		E1_KOG1660
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12304
Inparanoid	1	1.050	425	1.000	Inparanoid score	I1699
OMA	1	1.010	-	-		QHG52498
OrthoDB	1	1.010	-	-		D1009572at2759
OrthoFinder	1	1.000	-	-		FOG0004890
OrthoInspector	1	1.000	-	-		otm45553
orthoMCL	1	0.900	-	-		OOG6_105967
Panther	1	1.100	-	-	O	PTHR45850
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1564
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840