DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and Snx19

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_006242809.1	Gene:	Snx19 / 315478	RGDID:	1309857	Length:	900	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	88/372 - (23%)
Similarity:	143/372 - (38%)	Gaps:	115/372 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DDSNL-----------LNSPS-----TNNGA-TMEIASPTNPLATPPATGGAPAP-SGATNGSGS 52
            ||::|           |..||     ..:|| ::|.|.|...|::.|     |.| |.||....|
  Rat   369 DDASLTALLEEPEKPCLQRPSCLDKGLGSGACSLEPAVPPLSLSSSP-----PGPLSSATFSFES 428

  Fly    53 ATSPDSSSSAPATPAVLGENALHVEISDALSEKEK--------VKFTVHTRTTLPGFSKKD---- 105
            .:|||.       |.|:    .::.|:..::.:|.        ..:||...|.|.|.:...
  Rat   429 LSSPDG-------PVVI----QNLRITGTITAREHSGTGFHPYTLYTVKYETALSGENSSGLQQL 482

  Fly   106 --NNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPR---PDFDASREKLQRLGEGEGNMTKEEFK 165
              :.|.|::.||:.|..|:||..|...:|.....|:   ||...            |||..:..:
  Rat   483 AYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPF------------GNMDSDRVE 535

  Fly   166 KMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFV 230
            ..||.||:               |||:|.:.|.....:.::.||..:.|      .::|    ||
  Rat   536 ARKSLLES---------------FLRQLCAIPEIANSEEVQEFLALNTD------ARIA----FV 575

  Fly   231 KS--LGKTTDEILLSATVRDVNDFF-ENELQFLTEYHGHLREAALRTEKMTQRHK----DVGDSH 288
            |.  :....|::::||.|..:...| .:|.|..||   .|.||...::..|:..|    .:..|.
  Rat   576 KKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTE---ELSEAENESKPQTEGKKASKSRLRFSS 637

  Fly   289 QKISNALTQLSTTEK-------GN----------VETFVAKTAEIFE 318
            .||:.||:.....:|       ||          :|:|:.|..::.:
  Rat   638 SKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLQ 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	34/156 (22%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	28/115 (24%)
Snx19	XP_006242809.1	PXA	95..265	CDD:295366
		PX_SNX19	440..567	CDD:132803	34/153 (22%)
		Nexin_C	753..853	CDD:285792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910