DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx6 and SNX12

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001243114.1	Gene:	SNX12 / 29934	HGNCID:	14976	Length:	162	Species:	Homo sapiens

Alignment Length:	161	Identity:	36/161 - (22%)
Similarity:	72/161 - (44%)	Gaps:	31/161 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TSPDSSSSAPATPAVLGENALHVEISD----ALSEKEKVKFTVHTRTTLPGFSKKDNNVVRQHEE 114
            :.|...:.|...|:    |.|.::|.:    .:.......:.|..||.||.|..|::.|.|::.:
Human    14 SKPQDLTDAYGPPS----NFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPIFKLKESCVRRRYSD 74

  Fly   115 FVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATF 179
            |.||.:.:|.:   :..::||.|.:    |.:.:|...|: ||...:...::.:..||.
Human    75 FEWLKNELERD---SKIVVPPLPGK----ALKRQLPFRGD-EGIFEESFIEERRQGLEQ------ 125

  Fly   180 KKTVAMHEVFLRRLASHPVFRVDQHLKVFLE 210
                     |:.::|.||:.:.::.|.:||:
Human   126 ---------FINKIAGHPLAQNERCLHMFLQ 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	33/143 (23%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305
SNX12	NP_001243114.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		1/5 (20%)
SNX12	NP_001243114.1	PX_SNX12	27..158	CDD:132827	33/148 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910