DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and SNX10

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001305127.1	Gene:	SNX10 / 29887	HGNCID:	14974	Length:	227	Species:	Homo sapiens

Alignment Length:	162	Identity:	33/162 - (20%)
Similarity:	62/162 - (38%)	Gaps:	44/162 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 VEISDALSEKE-------KVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYII 133
            |.:.|...:||       ..:..:||.:..  |:.|.:.|.|::.|||||..|::.|     .::
Human    39 VWVRDPRIQKEDFWHSYIDYEICIHTNSMC--FTMKTSCVRRRYREFVWLRQRLQSN-----ALL 96

  Fly   134 PPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPV 198
            ...|..|                   :|..|..|.:....:     ::...: |.|||::..:.:
Human    97 VQLPELP-------------------SKNLFFNMNNRQHVD-----QRRQGL-EDFLRKVLQNAL 136

  Fly   199 FRVDQHLKVFLE-----YDQDLCAKPRKKMAI 225
            ...|..|.:||:     .|.:.|...:.|.::
Human   137 LLSDSSLHLFLQSHLNSEDIEACVSGQTKYSV 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	30/147 (20%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305
SNX10	NP_001305127.1	PX_SNX10	38..135	CDD:132808	26/127 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910