DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and Snx5

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_006235181.1	Gene:	Snx5 / 296199	RGDID:	1310190	Length:	404	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	199/376 - (52%)
Similarity:	270/376 - (71%)	Gaps:	7/376 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 ALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCP 137
            :|.::|.|||||::||||||||:||||.|...:.:|.||||:||||||.:.|..||||.||||.|
  Rat    30 SLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAP 94

  Fly   138 PRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVD 202
            .:||||..|||:|:||||||:||||||.|||.||||||||.|||||:.|||||:||:||||...|
  Rat    95 TKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKD 159

  Fly   203 QHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLSATVRDVNDFFENELQFLTEYHGHL 267
            ::..|||||||||..:.:....:||||.||:.|:.||:|.|. |::|:||||.|..||..|:..:
  Rat   160 RNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFSG-VKEVDDFFEQEKNFLINYYNRI 223

  Fly   268 REAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGNVETFVAKTAEIFERIKNLETRVASDQD 332
            :::..:.:|||:.||:|.|.:...:..|..|:..|...::.::.|.||:||:::.:|.||:||:|
  Rat   224 KDSCAKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDED 288

  Fly   333 LKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNLEKARSKNKDVHAPLEVQEAETAQAEAC 397
            |||.:.||||..:.:|||.||.||.:.|..||.:|:.|:|||.|:||      |:.|||.|.|.|
  Rat   289 LKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKD------VKLAETHQQECC 347

  Fly   398 EKFESMSACGKEELIGFRNRRVAAFKKSLVELSELEIKHAKTQYEYLRQSL 448
            :|||.:|...|||||.|:.:|||||:|:|:|:||||||||:.....|:..:
  Rat   348 QKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCI 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	93/138 (67%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	99/221 (45%)
Snx5	XP_006235181.1	PX_SNX5	29..169	CDD:132824	93/138 (67%)
Snx5	XP_006235181.1	BAR_SNX5	185..402	CDD:153347	99/221 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349187
Domainoid	1	1.000	220	1.000	Domainoid score	I2532
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	425	1.000	Inparanoid score	I1699
OMA	1	1.010	-	-		QHG52498
OrthoDB	1	1.010	-	-		D1009572at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45553
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45850
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1564
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.010