DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and C8orf44-SGK3

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001191102.1	Gene:	C8orf44-SGK3 / 100533105	HGNCID:	48354	Length:	496	Species:	Homo sapiens

Alignment Length:	157	Identity:	32/157 - (20%)
Similarity:	54/157 - (34%)	Gaps:	45/157 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DSSSSAPATPAVLGENALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDR 121
            |...|.|         ::.:..||...||:| :|||:  ..|....:.:..|.|::.||..|::.
Human     8 DYKESCP---------SVSIPSSDEHREKKK-RFTVY--KVLVSVGRSEWFVFRRYAEFDKLYNT 60

  Fly   122 IEENDDYAGYIIPPCPPRPD-FDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAM 185
            :::........||......| ||....|.:|.|..|
Human    61 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNE----------------------------- 96

  Fly   186 HEVFLRRLASHPVFRVDQHLKVFLEYD 212
               |::.|..:|.......::.||:.|
Human    97 ---FIQNLVRYPELYNHPDVRAFLQMD 120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	28/140 (20%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305
C8orf44-SGK3	NP_001191102.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		3/21 (14%)
		PX_CISK	12..120	CDD:132780	30/151 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	121..156		32/157 (20%)
		STKc_SGK3	165..490	CDD:270755
		Nuclear localization signal. /evidence=ECO:0000250	195..205
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910