DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and sgk3

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_012820716.1	Gene:	sgk3 / 100491891	XenbaseID:	XB-GENE-492582	Length:	490	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	58/308 - (18%)
Similarity:	98/308 - (31%)	Gaps:	133/308 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 PRPDFDASREKLQRLGEGEGNMTKE----------------EFKKM------------KSELEAE 174
            |:...|.|.::.:|:.:..|:.:::                |:.|:            :.:.:..
Frog   116 PKHQSDPSEDEDERVDQKNGSASRDVNLGPSGNPHAKPSDFEYLKLIGKGSFGKVVLTRGKRDGR 180

  Fly   175 YLA--TFKKTVAMHE-----------VFLRRLASHPVFRVDQHL------KVFLEYD-------- 212
            |.|  ..:|.|.:::           |.|:.: .|| |.|..|.      |:|...|
Frog   181 YYAVKVLQKNVILNKKEQRHIMAERNVLLKNV-KHP-FLVTLHYSFQTSDKLFFVLDFINGGELF 243

  Fly   213 -----QDLCAKPRKKMAIFGGFVKSLGKTTDEI-LLSATVRDVNDFFENELQFLTEYHGHLREAA 271
                 :...|:||   |:|  :...:|.....: .:....||:..  ||   .|.:..||:
Frog   244 FHLQRERYFAEPR---ALF--YAAEIGSALGYLHSIDIIYRDLKP--EN---ILLDSQGHI---- 294

  Fly   272 LRTEKMTQRHKDVGDSHQKISNA---LTQLSTTEKGNVETFVAK--------------------- 312
                .:|    |.|...:.|||:   ||...|.|....|..|.:
Frog   295 ----VLT----DFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNTVDWWCLGSVLYEMLHG 351

  Fly   313 --------TAEIFERI--KNLETR--------------VASDQDLKLG 336
                    ||.::|.|  |.|.||              :..|..|:||
Frog   352 LPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPKLRLG 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	20/120 (17%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	32/158 (20%)
sgk3	XP_012820716.1	PX_domain	7..114	CDD:383026
sgk3	XP_012820716.1	STKc_SGK3	159..484	CDD:270755	52/265 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910