DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx6 and snx19a

DIOPT Version :9

Sequence 1:	NP_001245939.1	Gene:	Snx6 / 34126	FlyBaseID:	FBgn0032005	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001124114.1	Gene:	snx19a / 100170806	ZFINID:	ZDB-GENE-060526-204	Length:	913	Species:	Danio rerio

Alignment Length:	374	Identity:	73/374 - (19%)
Similarity:	138/374 - (36%)	Gaps:	89/374 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PSGATNGSGSATSPDSSSSAPATPAVLGENAL---------------HVEISDALSEKEKVKFTV 92
            |......|...|...:|:|.|.:   ||.::|               :::|:..::.||:...:.
Zfish   440 PECTAEESPVQTLTHTSNSIPRS---LGLDSLVFENLENLDRPVAIKNLQITKTITAKEQRSSST 501

  Fly    93 HTRTTLP------GFSKKD--------NNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPR---P 140
            |..|...      |.|:..        :.|.|::.||:.|..|:||..|....|.....|:   |
Zfish   502 HPYTLYTVKYETGGDSESSASDQPVPCHMVNRRYSEFLNLQTRLEERTDLKKAIKNVKGPKKLFP 566

  Fly   141 DFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHL 205
            |...|            |...::.:..:|:||:               |||:|.:.|.....:.:
Zfish   567 DLPFS------------NPDSDKVEARRSQLES---------------FLRKLCTIPEAANSEEV 604

  Fly   206 KVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLSATVRDVNDFFENELQFLTEYHGHLREA 270
            :.||..:.|..|..:||.:  |..:..:.:...:.|.:|       |..:|.|..||.....|:.
Zfish   605 QEFLALNTDATASFQKKPS--GSRIDKMVENIVDTLKTA-------FPRSEPQSPTEEGDPQRKP 660

  Fly   271 ALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKG----NVETFVAKTAEIFERIKNLE----TRV 327
            .||.........:|......::.::::..|..:|    ::|.||.      |:.|.::    :..
Zfish   661 RLRFSSKIAPTLNVPSLQPNVTYSVSERCTVLRGFSLSDLEGFVE------EQEKQVDGGVRSHF 719

  Fly   328 ASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYE----AANRNLEK 372
            |..:.::....:....|.:|.|.|.:...:.||...:    ....|::|
Zfish   720 AGGRHVREQRPVEKRGRGADTALADIALNILCLLMKDQWSWLCTENIQK 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx6	NP_001245939.1	PX_SNX5_like	72..212	CDD:132802	33/171 (19%)
Snx6	NP_001245939.1	BAR_SNX5_6	228..452	CDD:153305	27/157 (17%)
snx19a	NP_001124114.1	PXA	91..267	CDD:280373
		PX_SNX19	484..611	CDD:132803	32/153 (21%)
		Nexin_C	766..867	CDD:285792	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910