DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8349 and CG8353

DIOPT Version :9

Sequence 1:	NP_609197.2	Gene:	CG8349 / 34124	FlyBaseID:	FBgn0032003	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001260233.1	Gene:	CG8353 / 34123	FlyBaseID:	FBgn0032002	Length:	170	Species:	Drosophila melanogaster

Alignment Length:	168	Identity:	87/168 - (51%)
Similarity:	116/168 - (69%)	Gaps:	8/168 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 SENLPHPQMLEEYTVAFCAVGEDGRELLEAALSARRCAYAPYSKFKVGAAFRAKC-GRIYAGCNI 163
            ::|...|:..|| .|.|.::....:|||.||...|:.||.|||.||||||||||. |:|:.|||:
  Fly     5 TKNFARPEKNEE-VVTFGSLDPSVQELLTAAFQVRQRAYVPYSGFKVGAAFRAKVDGKIFTGCNV 68

  Fly   164 ENVAFTPGNCAERCALAKGISEGEKKYTAGAVVAYHPDGFTTPCGVCRQFILEFIQNDIPIYIAK 228
            ||.|||||:||||.|:||.:|||..::.||||:||.|:.||||||||||||.||...|||||:|:
  Fly    69 ENAAFTPGSCAERTAIAKAVSEGATEFLAGAVLAYEPNVFTTPCGVCRQFIREFANADIPIYVAQ 133

  Fly   229 APP---PEQENCIPSIPDEAEVLVTSAYHLLPHSFNSF 263
            |..   .|::..:.|   :..|:.||.::|||.||:::
  Fly   134 AIDARIAEKQELLQS---DDPVMCTSIFNLLPSSFHTY 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8349	NP_609197.2	Cdd	122..260	CDD:223372	79/141 (56%)
CG8349	NP_609197.2	cytidine_deaminase-like	125..260	CDD:294193	79/138 (57%)
CG8353	NP_001260233.1	cyt_deam_tetra	28..165	CDD:273572	79/139 (57%)
CG8353	NP_001260233.1	cytidine_deaminase-like	29..167	CDD:294193	81/140 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473015
Domainoid	1	1.000	50	1.000	Domainoid score	I4357
eggNOG	1	0.900	-	-		E1_COG0295
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	47	1.000	Inparanoid score	I2658
Isobase	1	0.950	-	0	Normalized mean entropy	S1067
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1400471at2759
OrthoFinder	1	1.000	-	-		FOG0002702
OrthoInspector	1	1.000	-	-		mtm6519
orthoMCL	1	0.900	-	-		OOG6_100962
Panther	1	1.100	-	-	P	PTHR11644
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X545
	12	11.750