DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(var)205 and CBX4

DIOPT Version :9

Sequence 1:NP_476755.1 Gene:Su(var)205 / 34119 FlyBaseID:FBgn0003607 Length:206 Species:Drosophila melanogaster
Sequence 2:NP_003646.2 Gene:CBX4 / 8535 HGNCID:1554 Length:560 Species:Homo sapiens


Alignment Length:99 Identity:31/99 - (31%)
Similarity:50/99 - (50%) Gaps:9/99 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKK 85
            |..:|||.|..:|:|||:|||.:||:|:....||||||.|:....|:..::...:.|:.....|:
Human     8 EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKR 72

  Fly    86 ---------DRPSSSAKAKETQGRASSSTSTASK 110
                     ..|:.:.::....|...|||...:|
Human    73 GPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAK 106

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(var)205NP_476755.1 CHROMO 24..72 CDD:237991 22/47 (47%)
ChSh 141..202 CDD:197638
CBX4NP_003646.2 Interaction with BMI1 1..539 31/99 (31%)
Involved in interaction with H3C15 and H3C1. /evidence=ECO:0000269|PubMed:18927235 1..75 25/66 (38%)
CHROMO 10..62 CDD:214605 22/51 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 92..152 5/15 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 217..243
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 281..404
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 509..528
Involved in interaction with H3C15 and RNF2. /evidence=ECO:0000269|PubMed:18927235 531..556
CBX7_C <538..559 CDD:319236
Interaction with RNF2 540..560
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1628171at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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