DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)205 and cbx6a

DIOPT Version :9

Sequence 1:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	XP_021325056.1	Gene:	cbx6a / 799294	ZFINID:	ZDB-GENE-040808-26	Length:	488	Species:	Danio rerio

Alignment Length:	234	Identity:	60/234 - (25%)
Similarity:	93/234 - (39%)	Gaps:	82/234 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEE---------- 78
            :|.|.|:..|||||.:||.:||||:....:|||||.|:....||:.:|...:::|
Zfish    11 FAAEAILKSRVRKGHIEYLVKWKGWALKHSTWEPEENILDDRLIKAFEQKEREQELYGPKKRGPK 75

  Fly    79 ------KSAASKKDRP-------------------SSSAKAKETQGRASSSTSTA---------- 108
                  |:.|...|||                   ||||.:...|..:|||.|||
Zfish    76 PKNFVLKARAQSGDRPRSSYTRRTPSCTTAKPPTASSSASSATPQPSSSSSHSTAPTPRVHSLAA 140

  Fly   109 --------------SKR--KSEEPTAPS-GNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGAS 156
                          |:|  ...:|.|.| |:.|:.......:|:.:     .:|.::..::
Zfish   141 AHKLKKDIHRCHMMSRRPLPRSDPLANSTGSSSRHPISPFSETVRI-----LNRRVKPREV---- 196

  Fly   157 DNNGRLTFLIQFKGVDQAE-------MVPSSVANE-KIP 187
             ..||:  ::..|.:|::|       ..|.|.|.. |||
Zfish   197 -KRGRI--ILNLKVIDKSENGGMTSRRTPQSFAGRAKIP 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	22/47 (47%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	12/55 (22%)
cbx6a	XP_021325056.1	Chromo	11..60	CDD:306815	23/48 (48%)
cbx6a	XP_021325056.1	CBX7_C	432..463	CDD:319236
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920