DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Su(var)205 and Mphosph8

DIOPT Version :9

Sequence 1:NP_476755.1 Gene:Su(var)205 / 34119 FlyBaseID:FBgn0003607 Length:206 Species:Drosophila melanogaster
Sequence 2:NP_001347001.1 Gene:Mphosph8 / 75339 MGIID:1922589 Length:870 Species:Mus musculus


Alignment Length:160 Identity:47/160 - (29%)
Similarity:77/160 - (48%) Gaps:30/160 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 ESSAKVSDAEEE-EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNL-DCQDLIQQYE 71
            :.:..|.|:||: |:.:.||:|:|.:...||..|.::||||...::|||||.:| ||::::.::.
Mouse    43 KGTVAVGDSEEDGEDVFEVERILDMKCEGGKNLYKVRWKGYTSEDDTWEPEVHLEDCKEVLLEFR 107

  Fly    72 ASRKDEEKSAASKKD------------RPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKS 124
             .:..|.|:.|.:||            ..|.|.:..:|: ...|......|.|.:|.|:|...:.
Mouse   108 -KKLAENKAKAVRKDIQRLSLNNDIFEADSDSDQQSDTK-EDISPRKKKKKIKCKEETSPEDLRK 170

  Fly   125 KRT----------TDAEQDTIPVSGSTGFD 144
            |||          |:.|.    .|...|||
Mouse   171 KRTKMGKLKDKFKTELES----TSEIIGFD 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(var)205NP_476755.1 CHROMO 24..72 CDD:237991 19/48 (40%)
ChSh 141..202 CDD:197638 3/4 (75%)
Mphosph8NP_001347001.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 18..55 4/11 (36%)
CHROMO 58..109 CDD:214605 19/51 (37%)
Histone H3K9me3 binding. /evidence=ECO:0000250|UniProtKB:Q99549 80..87 4/6 (67%)
Neuromodulin_N <97..482 CDD:331332 25/106 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 129..175 12/46 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..234
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..300
ANK 605..729 CDD:238125
ANK 1 610..639
ANK repeat 613..641 CDD:293786
ANK repeat 643..674 CDD:293786
ANK 2 643..672
ANK repeat 676..705 CDD:293786
ANK 3 676..705
ANK 4 709..738
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1911
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1628171at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

Return to query results.
Submit another query.