DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)205 and cbx3b

DIOPT Version :9

Sequence 1:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	NP_001373276.1	Gene:	cbx3b / 567497	ZFINID:	ZDB-GENE-070628-2	Length:	194	Species:	Danio rerio

Alignment Length:	203	Identity:	76/203 - (37%)
Similarity:	115/203 - (56%)	Gaps:	19/203 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ESSAKVSDAEEEE--EEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQY- 70
            :.:.|...|||..  :|:||||||.|||..|||||||||||:.:.|||||||:||||.:||::|
Zfish     4 KQNVKNRKAEETTVVQEFAVEKIIRRRVNNGKVEYYLKWKGFTDAENTWEPEDNLDCPELIEEYL 68

  Fly    71 ---EASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQ 132
               ....::.|:......|.   ..:.||   ..|...:..:.::.:|......|:.....:||
Zfish    69 RNLTVLGQETEQEECQSLDH---EVQPKE---ELSELAADMAHQQPQEELIERTNEEVEEHNAE- 126

  Fly   133 DTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEER 197
              ||| |..|..   |.:.|:|.:|..|.|.|||::|..|:..::.:..|:::.|:|||.|||::
Zfish   127 --IPV-GQPGHP---EPDCIIGCTDQQGELMFLIKWKNTDEVALLAAVEASKRWPQMVIRFYEDK 185

  Fly   198 LSWYSDNE 205
            |:|:.|:|
Zfish   186 LTWHGDDE 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	34/51 (67%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	22/60 (37%)
cbx3b	NP_001373276.1	CD_CSD	20..68	CDD:421697	34/47 (72%)
cbx3b	NP_001373276.1	Chromo_shadow	136..188	CDD:396116	20/51 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8383
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.780