DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)205 and HP1c

DIOPT Version :9

Sequence 1:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	NP_651093.1	Gene:	HP1c / 42696	FlyBaseID:	FBgn0039019	Length:	237	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	60/185 - (32%)
Similarity:	100/185 - (54%)	Gaps:	49/185 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EEEEEYAVEKIIDRRV-RKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAA 82
            :.|..:.||:|:|:|: .:||||||:||:||...:||||||.|.||.:|||::|.||
  Fly     3 KNEPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEESR-------- 59

  Fly    83 SKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGL 147
                     ||:|              ||..::|......|.:                |::|||
  Fly    60 ---------AKSK--------------KRGEKKPKCEEIQKLR----------------GYERGL 85

  Fly   148 EAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYS 202
            |..:|:||:|..|.:.:|::::..|:.::|||:...||.|:|:|.:: ::::.||
  Fly    86 ELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSAQIVEKDPQMLIDYF-QKMAPYS 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	27/48 (56%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	20/60 (33%)
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	28/48 (58%)
HP1c	NP_651093.1	Chromo_shadow	89..134	CDD:279701	15/45 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455521
Domainoid	1	1.000	61	1.000	Domainoid score	I3809
eggNOG	1	0.900	-	-		E1_KOG1911
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I3624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D114392at33392
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	1	1.000	-	-		mtm4828
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
	10	9.900