DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)205 and Mphosph8

DIOPT Version :9

Sequence 1:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	NP_001017375.2	Gene:	Mphosph8 / 290270	RGDID:	1305133	Length:	851	Species:	Rattus norvegicus

Alignment Length:	173	Identity:	50/173 - (28%)
Similarity:	81/173 - (46%)	Gaps:	33/173 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ESSAKVSDAEEE-EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNL-DCQDLIQQYE 71
            :.:..|.|:||: |:.:.||:|:|.:...||..|.::||||...::|||||.:| ||::::.::.
  Rat    43 KGTVAVGDSEEDGEDVFEVERILDMKCEGGKNLYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFR 107

  Fly    72 ASRKDEEKSAASKKDRPSSSAKAK--------ETQGRASSSTSTASKRKS---EEPTAPSGNKSK 125
             .:..|.|:.|.:||....|....        :.||.....||...|:|.   :|..:|...:.|
  Rat   108 -KKVAENKAKAVRKDIQKLSLNNDIFEADSDIDQQGDTKEDTSPRKKKKKIKYKEDKSPDDLRKK 171

  Fly   126 RT----------TDAEQDTIPVSGSTGFD-----RGLEAEKIL 153
            |.          |:.|.    .|...|||     |.||.::.|
  Rat   172 RAKMGKLKDKFKTELES----TSEILGFDVKTKKRILEVKEEL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	19/48 (40%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	7/18 (39%)
Mphosph8	NP_001017375.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..54		3/10 (30%)
		CHROMO	58..109	CDD:214605	19/51 (37%)
		Histone H3K9me3 binding. /evidence=ECO:0000250\|UniProtKB:Q99549	80..87		4/6 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..174		10/40 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..302
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..428
		ANK	586..710	CDD:238125
		ANK 1	591..620
		ANK repeat	594..622	CDD:293786
		Ank_2	597..686	CDD:289560
		ANK repeat	624..655	CDD:293786
		ANK 2	624..653
		ANK repeat	657..686	CDD:293786
		ANK 3	657..686
		ANK 4	690..719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820