DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)205 and CBX6

DIOPT Version :9

Sequence 1:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	NP_055107.3	Gene:	CBX6 / 23466	HGNCID:	1556	Length:	412	Species:	Homo sapiens

Alignment Length:	207	Identity:	48/207 - (23%)
Similarity:	79/207 - (38%)	Gaps:	51/207 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKK 85
            |..:|.|.||.||:|||::||.:||||:....:|||||.|:....||..:|...::.|.....|:
Human     8 ERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKERERELYGPKKR 72

  Fly    86 D--------------------------RPSSSAKAKETQGRAS--------SSTSTASKRKSEEP 116
            .                          :||:||.:.:....|:        ......|:|....|
Human    73 GPKPKTFLLKARAQAEALRISDVHFSVKPSASASSPKLHSSAAVHRLKKDIRRCHRMSRRPLPRP 137

  Fly   117 TAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQ------AE 175
            ....|:...|.        |:|..:...|.:. .|:........|:  ::..|.:|:      |.
Human   138 DPQGGSPGLRP--------PISPFSETVRIIN-RKVKPREPKRNRI--ILNLKVIDKGAGGGGAG 191

  Fly   176 MVPSSVANEKIP 187
            ....::|..|:|
Human   192 QGAGALARPKVP 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	23/47 (49%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	9/53 (17%)
CBX6	NP_055107.3	CHROMO	10..62	CDD:214605	24/51 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..152		6/32 (19%)
		DNA_pol3_gamma3	<237..>331	CDD:331207
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..364
		CBX7_C	357..388	CDD:319236
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920