Protein Alignment Su(var)205 and Cdyl

DIOPT Version :10

• Sequence 1: NP_476755.1
• Gene: Su(var)205 / 34119
• FlyBaseID: FBgn0003607
• Length: 206
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 185
• Identity: 50/185 - (27%)
• Similarity: 86/185 - (46%)
• Gaps: 42/185 - (22%)

  Fly     9 ESSAKVSDAEEEEEEYAVEKIIDRRV-RKGKVEYYLKWKGYPETENTWEPENNL-DCQDLIQQYE 71
            ::|..:.|||.:     ||.|:|:|. :|||.||.::||||...::|||||.:| :|::.|..:.
Mouse    46 QASPAIQDAETQ-----VESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFN 105

  Fly    72 ASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTST---------------------ASKRKSEE 115
            ....:.:|..:..:...:|.:.|::...|::.||.:                     |:.:|..:
Mouse   106 RRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRK 170

  Fly   116 PTAPSGNKSKRTTDAEQDTI-------PVSGSTGFD--RGLEAEKI----LGASD 157
            ..||| ..:::..|..:..|       ||.|.|..|  :|...||:    .||.|
Mouse   171 NPAPS-LANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAED 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)205	NP_476755.1	CD_HP1a_insect	24..72	CDD:349300	22/49 (45%)
		CSD_HP1a_insect	146..198	CDD:349305	6/16 (38%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304		46/175 (26%)
		CD_CDY	57..106	CDD:349284	22/53 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158		6/47 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223		7/22 (32%)
		crotonase-like	339..535	CDD:119339
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589