DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8419 and trim24

DIOPT Version :9

Sequence 1:NP_609193.1 Gene:CG8419 / 34118 FlyBaseID:FBgn0031999 Length:921 Species:Drosophila melanogaster
Sequence 2:NP_001002870.2 Gene:trim24 / 442869 ZFINID:ZDB-GENE-030131-5913 Length:961 Species:Danio rerio


Alignment Length:425 Identity:93/425 - (21%)
Similarity:151/425 - (35%) Gaps:144/425 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   308 CGICLDVYT--DPRTLHCLHSFCLQCLVSENFKDESLWDQDQARSEEPSNYSLRSEMGGSSAELT 370
            |.:|...::  :|:.|.||||||.:||.:.:                                  
Zfish    51 CPVCKLSFSSREPKLLPCLHSFCKRCLPAHS---------------------------------- 81

  Fly   371 ATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRSTSSIGTRFTGSFASEVSTRCIRCHTCNYP- 434
               |||                                 ||..|   |.::|  .|||..|... 
Zfish    82 ---SPA---------------------------------GTTST---AKQLS--MIRCPVCQQEC 105

  Fly   435 TDLSLGGVRQLPQNYLLVRRIEVLRLQAGEDVISRVWCSLCTEEISATYHCISCTLNLCTLCKEA 499
            .|:      ::..|:.:...:||   .:.....|...|..|.:...|:..|:.|...||..|.:|
Zfish   106 MDV------EVLDNFFVKDSVEV---PSSTMEKSCQLCMSCDDNTEASGFCVECVEFLCVTCIDA 161

  Fly   500 HERQRSTASHRMRSILELRRARKQKQQQMGLGDSSKLVLRCGIHTNFELKAFCTNCRQLACTDCL 564
            |:|.:.|..|.:|.|.|:        ....:|.|::..:.|.||....||.||..|.:|.|.||.
Zfish   162 HQRVKFTRDHTVRQITEM--------SSEAMGASTQKPVFCDIHRQEPLKLFCETCDRLTCRDCQ 218

  Fly   565 VILHKGHRHETISRAIGHQGKLLKEATDQTRPLCQYAEHSIERLNAIARGINDRCDDIQTQVERY 629
            ::.||.|.::.:..|..:..:.|:..|      ||..    |:..||        :|:...:...
Zfish   219 LLKHKDHNYQFLEDAYRNHKEHLENMT------CQLQ----EKKKAI--------EDVTNTINNG 265

  Fly   630 MQQYMDALTVHRKTLLQQISRA---------RESK-----VEVVLKQQLDLEKRTQQAMDAVRFS 680
            :||    :..:|||:..:|.::         |:.|     :|.:.|....|.|:.||  |....|
Zfish   266 LQQ----VDENRKTVANEIKKSICNLIMEINRKGKLLVNQLEAITKDHEILLKKQQQ--DVTSLS 324

  Fly   681 QELCEIGADVEILSYVT--------ILLRRLEYCQ 707
            ..|..:   :....:.|        :..:||..||
Zfish   325 THLDHV---INFTKWATASNSGTALLYCKRLITCQ 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8419NP_609193.1 RING 308..>334 CDD:214546 12/27 (44%)
zf-B_box 537..576 CDD:279037 15/38 (39%)
iSH2_PI3K_IA_R 583..703 CDD:304922 26/141 (18%)
Filamin 748..846 CDD:279024
IG_FLMN 751..849 CDD:214720
trim24NP_001002870.2 zf-RING_5 51..103 CDD:291308 24/126 (19%)
BBOX 132..176 CDD:197662 14/43 (33%)
BBOX 192..230 CDD:237988 15/37 (41%)
iSH2_PI3K_IA_R 237..363 CDD:304922 30/147 (20%)
TNG2 <604..744 CDD:227367
PHD_SF 699..744 CDD:304600
Bromo_tif1_like 771..877 CDD:99934
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.