DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8419 and Rnf207

DIOPT Version :9

Sequence 1:NP_609193.1 Gene:CG8419 / 34118 FlyBaseID:FBgn0031999 Length:921 Species:Drosophila melanogaster
Sequence 2:NP_001028661.2 Gene:Rnf207 / 433809 MGIID:2684989 Length:635 Species:Mus musculus


Alignment Length:429 Identity:79/429 - (18%)
Similarity:133/429 - (31%) Gaps:128/429 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   306 LKCGICLDVYTDPRTLHCLHSFCLQCLVSENFKDESLWDQDQARSEEPSNYSLRSEMGGSSAELT 370
            |.|.:|...|..|..|.|.|.||..||                                      
Mouse    23 LVCPLCHGQYERPCLLDCFHDFCTGCL-------------------------------------- 49

  Fly   371 ATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRSTSSIGTRFTGSFASEVSTRCIRCHTCNYPT 435
                    ||.:                 :||:.|                      |..|.:.|
Mouse    50 --------RGRA-----------------TDGRLS----------------------CPLCQHQT 67

  Fly   436 DLSLGGVRQLPQNYLLVRRIEVLRLQAGEDVISRVWCSLCTEEIS-----ATYHCISCTLNLCTL 495
              .:.|...||.    |.|:....:.:..|....|.|:.|..|.|     .||.|.:|...||..
Mouse    68 --LVKGPSGLPP----VDRLLQFLVDSSGDGSEAVRCANCDLECSQQDAETTYFCNTCGQPLCAR 126

  Fly   496 CKEAHERQRSTASHRMRSILELRRARKQKQQQMGLGDSSK-LVLRCGIHTNFELKAFCTNCRQLA 559
            |:|...|.|..|.|.:                :.||..|: ::.:|.:|:...: .|.|:.:.|.
Mouse   127 CREETHRARMFARHDI----------------VALGQRSRDVIQKCTLHSEPYI-MFSTDKKSLL 174

  Fly   560 CTDCLVILHKGHRHETISRAIGH-QG-KLLKEATDQTRPLCQYAEHSIERLNAIARGINDRCDDI 622
            |..|...:....|...:.....: || :.|::|....:.|....:.:|..|.::...:.....:.
Mouse   175 CIRCFRDMQGESRAHCVDLESAYVQGCERLEQAVLAVKALQTATKEAIALLQSMVEEVRHSAAEE 239

  Fly   623 QTQVERYMQQYMDALTVHRKTLLQQISRARESKVEVVLKQQLDLEKRTQQAMDAVRFSQELC--- 684
            :..:........|.:...:..|||.:....|.| :...|:||   ......:..::....:|   
Mouse   240 EAAIHALFGSMQDRMAERKALLLQTVQSQYEEK-DKAFKEQL---THLASLLPTLQVHLVICSSF 300

  Fly   685 -EIGADVEILSYVTILLRRLEYC----QQFKPPVDPKIS 718
             .:.:..|.|.....|:.||:..    .:.:|....||:
Mouse   301 LSLASKAEFLDLGYELMERLQGIVTRPHRLRPAQSSKIA 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8419NP_609193.1 RING 308..>334 CDD:214546 11/25 (44%)
zf-B_box 537..576 CDD:279037 8/38 (21%)
iSH2_PI3K_IA_R 583..703 CDD:304922 20/124 (16%)
Filamin 748..846 CDD:279024
IG_FLMN 751..849 CDD:214720
Rnf207NP_001028661.2 RING 25..63 CDD:214546 17/122 (14%)
zf-B_box 93..145 CDD:279037 17/67 (25%)
iSH2_PI3K_IA_R 202..321 CDD:304922 19/122 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 553..635
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D489543at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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