Protein Alignment CG8419 and trim9

DIOPT Version :10

• Sequence 1: NP_609193.1
• Gene: CG8419 / 34118
• FlyBaseID: FBgn0031999
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_005157040.1
• Gene: trim9 / 336099
• ZFINID: ZDB-GENE-030131-8043
• Length: 730
• Species: Danio rerio
• Alignment Length: 678
• Identity: 134/678 - (19%)
• Similarity: 234/678 - (34%)
• Gaps: 162/678 - (23%)

  Fly   304 DDLKCGICLDVYTDPRTLHCLHSFCLQC----LV---------SENFKDESLWDQDQARSEEPSN 355
            ::|||.:|...:.:|..|.|.|:.||.|    ||         |.......:.|.|....::.|.
Zfish     6 EELKCPVCGSFFREPIILPCSHNICLACARNILVQTPDAESPQSSRASGSGVSDYDYLDLDKMSL 70

  Fly   356 YS-LRSEMGGSSAELTATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRSTSSIGTRFTGSFAS 419
            || ..|..|.....::|..:|.::..:..         |:...|....:::...: ...||....
Zfish    71 YSEADSGYGSYGGFVSAPTTPCQKSPNGV---------RVFPPSMPPPQQAQHHL-LPHTGVLPP 125

  Fly   420 EVSTRCIRCHTCNYPTDLSLGGVRQLPQNYLLVRRIEVLRLQAGEDVISR--------VWCSLCT 476
            .....|:.|..|:....|...|:|..|:|.:|            |.|:.|        :.|.||.
Zfish   126 VPRNSCLTCPQCHRSLTLDDRGLRGFPKNRVL------------EGVVDRYQQSKAAALKCQLCE 178

  Fly   477 EE-ISATYHCISCTLNLCTLCK-EAHERQRSTASHRMRSILELRRARKQKQQQMGLGDSSKLVLR 539
            :. ..||..|..|.:..|..|: ..|..:...|.||:....:.|.:|:.         |.:.:..
Zfish   179 KSPREATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRISRRA---------SPRKIST 234

  Fly   540 CGIHTNFELKAFCTNCRQLACTDCLVILHKGHRHETIS-RAIG-----HQGKL------------ 586
            |..|....|..:|..|:...|..||    :..:|.|.. :|:|     |:|:|
Zfish   235 CTEHELENLSMYCVQCKTPVCYQCL----EDGKHSTHEVKALGAMWKLHKGQLSQALNVLSDRAT 295

  Fly   587 -LKEATDQTRPLCQYAEHSIERLNAIARGINDRCDDIQTQVERYMQQYMDALTVHRKTLLQQISR 650
             .||...|.|.:.|:.:.:.....|.   :..:||.:           ::||...:..||.::::
Zfish   296 EAKEFLVQLRNMVQHIQENGVEFEAC---LVAQCDAL-----------IEALNRRKAQLLSRVTK 346

  Fly   651 ARESKVEVVLKQQLDLEKRTQQAMDAVRFSQELCEIGADVEILSYVTILLRRLEYC--QQFKPPV 713
            ..|.|:.||..|......:.:|....:.:..|:.:.......|.....|:||:...  |..|..:
Zfish   347 EHEHKLSVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHMTENQWGKGSL 411

  Fly   714 DPKISD----SLHFLPKIRAPSTKD--QRDIPLYGII------------TMQVVEPSLCTLEWEG 760
            .|::|.    :|...|.::.....|  |..:|...|:            |:...:|.|.|:..:|
Zfish   412 TPRMSSDFDLTLDSGPLLQTIHQLDFVQMKVPAAPILQLEECCTQTSSATLSWKQPPLSTIAVDG 476

  Fly   761 FSQLRLHKKADLLLHSRDADGVSL--CHGGLEINCMLKYKDSSSKFLPVEVSDNRDGTYNISFTP 823
            :           :|...|..|...  .:.|.|:.|.:.....:|.:      .:|...:|.|...
Zfish   477 Y-----------ILELDDGTGGQFREVYVGTEMICTVDGLHFNSTY------KSRVKAFNSSGVG 524

  Fly   824 DAQGTLILTITINDRPIKGGP-------FTFQARQVRPHTGIYHCCSFCSGKGNRNVMCSCEGH- 880
            ....||::..:....|..|..       |||.:....|...:          .|.|:..:|..:
Zfish   525 QYSKTLVMQTSEMSLPSYGSQTLATVAWFTFDSASAHPDIIL----------SNDNLTVTCNSYD 579

  Fly   881 ---MPGYSGCGHG----------HAGHP 895
               :.|.:|...|          :..||
Zfish   580 DRVVMGNTGFSRGVHYWEMTIDRYDNHP 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8419	NP_609193.1	RING_Ubox	304..>345	CDD:473075	14/53 (26%)
		Bbox1_TRIM45_C-X	470..514	CDD:380867	13/45 (29%)
		Bbox2	539..576	CDD:380814	9/36 (25%)
		CC_brat-like	583..703	CDD:475168	24/132 (18%)
		Filamin	748..846	CDD:395505	18/106 (17%)
trim9	XP_005157040.1	RING-HC_TRIM9	5..49	CDD:438413	13/42 (31%)
		Bbox1_TRIM9_C-I	172..218	CDD:380901	13/45 (29%)
		Bbox_SF	229..277	CDD:469587	12/51 (24%)
		BBC	279..405	CDD:128778	26/139 (19%)
		FN3	443..534	CDD:238020	19/107 (18%)
		SPRY_PRY_TRIM67_9	545..715	CDD:293947	12/73 (16%)