Protein Alignment CG8419 and Pml

DIOPT Version :10

• Sequence 1: NP_609193.1
• Gene: CG8419 / 34118
• FlyBaseID: FBgn0031999
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: NP_001414234.1
• Gene: Pml / 315713
• RGDID: 1562602
• Length: 886
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 92/524 - (17%)
• Similarity: 160/524 - (30%)
• Gaps: 209/524 - (39%)

  Fly   280 PPVSPSPSITLRPSTPPENTVIFTDD---LKCGICLDVYTDPRTLHCLHSFCLQCLVSENFKDES 341
            ||..||.... ...:|.|..:  .::   |:|..|......|:.|.|||:.|..||
  Rat     3 PPEEPSEDHE-HSQSPAEQAI--KEEFQFLRCPGCQTQAKCPKLLPCLHTLCSGCL--------- 55

  Fly   342 LWDQDQARSEEPSNYSLRSEMGGSSAELTATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRST 406
                     |.|.
  Rat    56 ---------EAPG---------------------------------------------------- 59

  Fly   407 SSIGTRFTGSFASEVSTRCIRCHTCNYPTDLSLGGVRQLPQNYL--LVRRIEVLRLQAGEDVISR 469
                               ::|..|..|...: .....|...:.  |.||:.|.|    :.|.::
  Rat    60 -------------------LQCPICQAPGSAN-ANAEALDNVFFESLQRRLAVFR----QIVDAQ 100

  Fly   470 VWCSLCTEEISATYHCISCTLNLCTLCKEAHERQRSTASHRMRSILELRRARKQKQQQMGLGDSS 534
            ..|:.|.|  .|.:.|..|...:|..|.:||:..   ..|..|.:.|||    ....:..|..:.
  Rat   101 AACTRCKE--LADFWCFECEQLMCGKCFDAHQWY---LKHEARPLAELR----DNSVREFLDSTR 156

  Fly   535 KLVLRCGIHTNFELKA----FCTNCRQLACTDCLVILHKGHRH----------------ETISRA 579
            |..:.|. :||....|    :|..|.:..|.:| .:|.:.|.|                .|:::|
  Rat   157 KSNIFCS-NTNHRTPAQTNIYCRGCAKPLCCEC-ALLDRNHSHLQCEIGKEIQQLHEELGTMTQA 219

  Fly   580 IGHQGKLLKEATDQTRPLCQYAEHSIERLNAIARGINDRCDDIQTQVERYMQQYMDALTVHRKTL 644
            :..||:....|..|.        ||     ||.: ::|...|.:.|:...::|.::.:....:.|
  Rat   220 LEEQGRTFDSAHAQM--------HS-----AIGQ-LDDARSDTEKQIRARVRQVIEHVQAQEREL 270

  Fly   645 LQQISRARESKVEVVLKQQLDLEKRTQQAMDAVRFSQELCEIGADVEILSYVTILLRRLEYCQQF 709
            |:.::                           ||:.::..||...   |.::..:|:|:
  Rat   271 LEAVN---------------------------VRYQRDYQEIAGQ---LGHLEAVLQRI------ 299

  Fly   710 KPPVDPKISDSLHFLPKIRAPSTKDQRDIPLYGIITMQVVEPSLCTLEWE------------GFS 762
                  :...:|....|:.|   .:|..:.::|.:     ..:||.|..|            ||.
  Rat   300 ------RTGGALVKRMKLYA---SEQEVLDMHGFL-----RKALCRLRQEEPQNHKVQLRTSGFE 350

  Fly   763 QLRL 766
            :.:|
  Rat   351 EFKL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8419	NP_609193.1	RING_Ubox	304..>345	CDD:473075	11/43 (26%)
		Bbox1_TRIM45_C-X	470..514	CDD:380867	12/43 (28%)
		Bbox2	539..576	CDD:380814	11/56 (20%)
		CC_brat-like	583..703	CDD:475168	20/119 (17%)
		Filamin	748..846	CDD:395505	7/31 (23%)
Pml	NP_001414234.1	None