DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8419 and RNF152

DIOPT Version :9

Sequence 1:NP_609193.1 Gene:CG8419 / 34118 FlyBaseID:FBgn0031999 Length:921 Species:Drosophila melanogaster
Sequence 2:NP_775828.1 Gene:RNF152 / 220441 HGNCID:26811 Length:203 Species:Homo sapiens


Alignment Length:165 Identity:36/165 - (21%)
Similarity:62/165 - (37%) Gaps:31/165 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   690 VEILSYVTILLRRLEYC-QQFKPPVDPKISDSLH-----FLPKIRAPSTKDQRDIPLYGIITMQV 748
            :|.||..::|  ..:.| ..:.|...||:.|..|     .|.::|. |.||.|.....|:..:. 
Human     1 METLSQDSLL--ECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRT-SQKDVRCPWCRGVTKLP- 61

  Fly   749 VEPSLCTLEWEGFSQLRLHKKADLLLHSRDADGVSLCHGGLEINCMLKYKDSSSKFLPVEVSDNR 813
                      .|||..:|....::|.      .:::.|........:|...:....||:.:|..|
Human    62 ----------PGFSVSQLPDDPEVLA------VIAIPHTSEHTPVFIKLPSNGCYMLPLPISKER 110

  Fly   814 ---DGTYNISFTPDAQ--GTLILTITINDRPIKGG 843
               .|.......|.:|  ...::||....:|::||
Human   111 ALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGG 145

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8419NP_609193.1 RING 308..>334 CDD:214546
zf-B_box 537..576 CDD:279037
iSH2_PI3K_IA_R 583..703 CDD:304922 4/12 (33%)
Filamin 748..846 CDD:279024 19/101 (19%)
IG_FLMN 751..849 CDD:214720 19/98 (19%)
RNF152NP_775828.1 RING-HC_RNF152 11..55 CDD:319462 12/44 (27%)
Necessary for interaction with RRAGA. /evidence=ECO:0000269|PubMed:25936802 106..165 10/40 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D489543at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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