DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8419 and F43G6.8

DIOPT Version :9

Sequence 1:	NP_609193.1	Gene:	CG8419 / 34118	FlyBaseID:	FBgn0031999	Length:	921	Species:	Drosophila melanogaster
Sequence 2:	NP_496523.1	Gene:	F43G6.8 / 174815	WormBaseID:	WBGene00009660	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	45/208 - (21%)
Similarity:	74/208 - (35%)	Gaps:	53/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 ERQRSTASHRMRSILELRRARKQ---KQQQMGLGDSSKLVLRCGIHT----------NFELKAFC 552
            |.|:|.....::..||..|.|:.   |.:|:.             ||          ..|.....
Worm    29 EEQQSQEIRNLKRKLEEARQREDKYIKNEQLH-------------HTAMRSKQQRIERMEKSMES 80

  Fly   553 TNCRQLACTDCLVILHKGHRHETISRAIGHQGKLLKEATDQTRPLCQYAEHSIERLN-------A 610
            || |::..|.|.:     :..|.|...:..:.|::.:..|.........|...:.|.       |
Worm    81 TN-RKMYATQCRL-----NDMENIYDDLEMESKIMADFIDHYYDSRNITEEDRDELQDKLDEEAA 139

  Fly   611 IARGINDRCDDIQTQVERYMQQYMDALTVHRKTLLQQISRARESKVEVVLKQQLDLEKRTQQAMD 675
            ..|.:.||..::     |:..:||..:...||    :.:..|:..:|  |.:||..|   ||.:.
Worm   140 NYRDLEDRIKEV-----RHRDRYMKTVETERK----RTTFYRKKMLE--LAEQLQFE---QQEVT 190

  Fly   676 AVRFSQELCEIGA 688
            ......:||||.|
Worm   191 GETPLWKLCEICA 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8419	NP_609193.1	RING	308..>334	CDD:214546
		zf-B_box	537..576	CDD:279037	9/48 (19%)
		iSH2_PI3K_IA_R	583..703	CDD:304922	26/113 (23%)
		Filamin	748..846	CDD:279024
		IG_FLMN	751..849	CDD:214720
F43G6.8	NP_496523.1	SMC_prok_B	<15..>188	CDD:274008	39/191 (20%)
F43G6.8	NP_496523.1	RING-HC_TRIM32_C-VII	198..243	CDD:319501	5/6 (83%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010