Protein Alignment CG8419 and trim3

DIOPT Version :9

• Sequence 1: NP_609193.1
• Gene: CG8419 / 34118
• FlyBaseID: FBgn0031999
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_031753313.1
• Gene: trim3 / 100497041
• XenbaseID: XB-GENE-5826034
• Length: 790
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 105/554 - (18%)
• Similarity: 188/554 - (33%)
• Gaps: 156/554 - (28%)

  Fly   306 LKCGICLDVYTDPRTLHCLHSFCLQCLVSENFKDESLWDQDQARSEEPSNYSLRSEMGGSSAELT 370
            |.|.|||:.|..|:.|.|||:||.:||.|
 Frog    64 LICSICLERYHIPKVLPCLHTFCERCLQS------------------------------------ 92

  Fly   371 ATVSPARQRGSSFTLRRKKSMDRLVIRSKSDGKRSTSSIGTRFTGSFASEVSTRCIRCHTCNYPT 435
             .:.|     .|.||                                         .|..|...:
 Frog    93 -YIPP-----QSLTL-----------------------------------------SCPVCRQTS 110

  Fly   436 DLSLGGVRQLPQNYLLVRRIEVLRLQAGEDVISRVWCSLCTEEISATYHCISCTLNLCTLCKEAH 500
            .|...||..|..|:.:...:|||
 Frog   111 ILPEKGVSALQNNFFITNLMEVL------------------------------------------ 133

  Fly   501 ERQRSTASHRMRSILELRRARKQKQQQMGL---GDSSKLVLRCGIHTNFELKAFCTNCRQLACTD 562
              |||..|.|              |:|..|   |..:...|.|..|....::.:|..|....|.:
 Frog   134 --QRSPESGR--------------QEQSVLPSEGQEAGTPLSCPNHQGKTMEYYCGPCETAMCVE 182

  Fly   563 CLVILHKGHRHETISRAIGHQGKLLKEATDQTRPLCQYAEHSIERLNAIARGINDRCDDIQTQVE 627
            |....|:.|....:...:......|:...:..|........:|:.::.|:|.:::|.:....::.
 Frog   183 CTEGEHREHCTVPLRDVVEQHKASLRNQLESIRSRIPQLTSAIDLVSDISRQLSERKNSAVNEIC 247

  Fly   628 RYMQQYMDALTVHRKTLLQQISRARESKVEVVLKQQLDLEKRTQQAMDAVRFSQELCEIGADVEI 692
            ...::...||...:..|||.:......|.:|:..|...|.:.......:|||:::....|::.|:
 Frog   248 SAFEELEKALQQRKSALLQDLEAICVGKQKVLQSQLSSLRQGLDNMESSVRFTEQALGHGSETEV 312

  Fly   693 LSYVTILLRRLEYCQQFKPPVDPKISDSLHFLPKIRAPSTKDQRDIPLYG--IITMQVVEPSLCT 755
            |.....:..||........|:.|:.:..|.|    |..:...:|.:...|  :.|..|...|:.|
 Frog   313 LLVRKQMSERLNELAARDFPLHPQQNPQLEF----RVETEGLRRSLQNLGALLTTNAVAYASVAT 373

  Fly   756 LEWEGFSQLRLHKKADLLLHSRDADGVSLCHGGLEINCMLKYKDSSSKFLPVEVSDNRDGTYNIS 820
              .||..|..:.::..:.:.::|.||..:..|...:...:...|..::  ..||:||::|||.:.
 Frog   374 --GEGLRQALVGQQTSVTVTTKDMDGELVRSGNATLKAQITGPDGGAQ--EGEVTDNKNGTYEVL 434

  Fly   821 FTPDAQGTLILTITINDRPIKGGPFTFQARQVRP 854
            :|...:|..:|::.:..:|::|.|  ::.|.::|
 Frog   435 YTLRVEGEHLLSLRLYGQPLRGSP--YRVRAIKP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8419	NP_609193.1	RING	308..>334	CDD:214546	14/25 (56%)
		zf-B_box	537..576	CDD:279037	9/38 (24%)
		iSH2_PI3K_IA_R	583..703	CDD:304922	21/119 (18%)
		Filamin	748..846	CDD:279024	24/97 (25%)
		IG_FLMN	751..849	CDD:214720	23/97 (24%)
trim3	XP_031753313.1	RAD18	54..>150	CDD:227719	38/226 (17%)
		RING_Ubox	63..107	CDD:418438	21/125 (17%)
		Bbox2_TRIM3_C-VII	154..198	CDD:380883	9/43 (21%)
		BBC	203..328	CDD:128778	23/124 (19%)
		IG_FLMN	369..463	CDD:214720	23/99 (23%)
		NHL_TRIM2_like	513..790	CDD:271330

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920