Protein Alignment SLC5A11 and DUR3

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_011847.1
• Gene: DUR3 / 856370
• SGDID: S000001008
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 659
• Identity: 146/659 - (22%)
• Similarity: 236/659 - (35%)
• Gaps: 226/659 - (34%)

  Fly    20 AVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFP 84
            |||.||:||:|    |.  :|:.:.::..||                     |:....|::|...
Yeast    22 AVFAGMMVLTT----YL--LKRYQKEIITAE---------------------EFTTAGRSVKTGL 59

  Fly    85 VAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVY-------IPVFSALQV-- 140
            ||.::::|:|...|:|.::::.|              ..||...|.|       |..|:.|.:
Yeast    60 VAAAVVSSWIWCSTLLTSSTKEY--------------ADGIFGGYAYAAGACFQIIAFAILAIKT 110

  Fly   141 ----GSSYEYLEM---RFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIV 198
                .:::.|||:   |:..:......|..|...||....::...:...:.::|:|......::.
Yeast   111 KQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLP 175

  Fly   199 VVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVL------FD---DAAKGGR 254
            |..|.||..|||||...||.....|:.:.||..|.  .|||.. :||      :|   :|||  |
Yeast   176 VGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAF--KVYATS-DVLGSPGKVYDLVREAAK--R 235

  Fly   255 LIFNNTNPSPYVRHTVWSV-------LIGGF-------SYWTSFNAVNQTMVQRYMSLPSLKKAR 305
            ...:......|:..|..|.       |||.|       .||.  .|::.:        |:
Yeast   236 HPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWN--KAISAS--------PA----- 285

  Fly   306 ASMAIFTIGVAAFVSVCCYVGLLI------------YEMYKDCDPL-----SAGLITHDDQLLPL 353
            ||:..:.||..|:.:|...:.|.:            :..|.  |||     ::||:      ||.
Yeast   286 ASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYP--DPLTSFQANSGLV------LPA 342

  Fly   354 FVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTV 418
            ..:..:|....::.|.:  ||.|..|::|..|.:.|.|...||.|
Yeast   343 AAIAIMGKGGAVASLLM--IFMAVTSAMSAELIAVSSVFTYDIYR-------------------- 385

  Fly   419 IVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIASALLAG 483
                      .::..:.||...|.||..|.   ..|||               |:.|.:..|..|
Yeast   386 ----------EYIDPRASGKKLIYTSHVAC---IFFGL---------------AMSGFSVGLYYG 422

  Fly   484 WISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVI- 547
            .||.|..:.:....::|..|||.:..|..::.|                          ||.|:
Yeast   423 GISMGYIYEMMGIIISSAVLPVVLTLCSKDMNL--------------------------VAAVVS 461

  Fly   548 -VVG---ALVS-LVTKPTNMKTLDPD---------------LISPVIHRFLP--KECFSGRNLHA 590
             ::|   |::| ||...:..|.|..|               |:||.|  |:|  ...|..:|...
Yeast   462 PILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAI--FIPILTYVFKPQNFDW 524

  Fly   591 QAHKNLLNV 599
            :..|::..|
Yeast   525 EKMKDITRV 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	131/597 (22%)
DUR3	NP_011847.1	SLC5sbd_DUR3	14..517	CDD:271370	142/641 (22%)