Protein Alignment SLC5A11 and slc5a6b

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_005158632.1
• Gene: slc5a6b / 796312
• ZFINID: ZDB-GENE-050913-86
• Length: 603
• Species: Danio rerio
• Alignment Length: 596
• Identity: 186/596 - (31%)
• Similarity: 307/596 - (51%)
• Gaps: 53/596 - (8%)

  Fly    14 FGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMS---EYLL 75
            |..:||.:|..::|.|.|.|:|:.                           |...:.|   |:|:
Zfish     9 FTVIDYVIFGLLLVASMSIGLYYA---------------------------FTGGRQSTTQEFLI 46

  Fly    76 GSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQV 140
            ..|::|..|:::||:|::.|.|.|:||.:|:|.:|||||||..:.:|..:..::::||:|..|.:
Zfish    47 ADRSMKCLPLSLSLMATFQSAVAIIGTPAEVYAHGTQYWFIGCSYVLGLLIPAHIFIPLFYRLHL 111

  Fly   141 GSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYT 205
            .|.|:|||:||...||...:..||...::::...:|.||:|||.|:|.:|....:...:||..||
Zfish   112 TSVYQYLELRFCKAVRICGTVTFIFQMVIYMGVGIYTPALALNAVTGFHLWGAVLATGLVCTLYT 176

  Fly   206 FVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTV 270
            .:||:||||.||.:|.:|||...|||.|:....|.||:..:.....|||:...:.||.|.||||.
Zfish   177 ALGGLKAVVWTDVFQTVVMFTGQLAVIIVGVHQAGGLSEAWGKVRDGGRISGIDLNPDPTVRHTF 241

  Fly   271 WSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARAS--MAIFTIGVAAFVSVCCYVGLLIYEMY 333
            |::.:||.....|...|||..||||:|..:.::|..|  |....:.:|..:|  |.:||:::..|
Zfish   242 WTLAVGGVFLMLSLYGVNQAQVQRYLSSRTEREAVMSCYMVFPCLQLALLLS--CLMGLVMFACY 304

  Fly   334 KDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVR 398
            ....|:....||..||::..||:..:.:..|:.|||:|.:|.|:||::|...||.:.|.:.|:::
Zfish   305 GQNSPVEQQYITSKDQMVLYFVMDMLQNFPGLPGLFVACLFSASLSTISSAFNSLATVTMVDLIK 369

  Fly   399 GCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQL-SGILSICTSMTAIAAGTTFGLFTLGML 462
            ..:.|  :|..:|:|.|...:..|.:.|::.:::..: |.:|....|:..:..|...|||.||:.
Zfish   370 PHYSM--TEARATLLSKLLALSYGIICLAMAYLVHLMNSSVLQAALSIFGMIGGPLLGLFCLGIF 432

  Fly   463 VPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLP-----VSVEGCVGNVT-LRENIW 521
            .|.||::|...|..|..|:|.|:..|...|    .:.|..:|     ::|.....|:| ....:.
Zfish   433 FPCANSIGAVTGLSAGLLMAFWVGIGGFLT----RMPSPVIPLLNSTITVPDVSENITAATAELE 493

  Fly   522 VDEEQ--VFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVI---HRFL-PK 580
            .|...  :...|.|||.|.:.:...||::||.::|.:|.||....:....:.||:   ..:| |.
Zfish   494 ADSRSAGLHGFYSLSYMWYSALSSCTVLIVGLIISCITGPTKGDDVASGTVYPVVKTAQSYLKPS 558

  Fly   581 ECFSGRNLHAQ 591
            .|......|.|
Zfish   559 TCCKTTAEHKQ 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	175/552 (32%)
slc5a6b	XP_005158632.1	SLC5-6-like_sbd	9..532	CDD:444915	176/557 (32%)