Protein Alignment SLC5A11 and Slc5a2

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_072112.2
• Gene: Slc5a2 / 64522
• RGDID: 620217
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 116/482 - (24%)
• Similarity: 206/482 - (42%)
• Gaps: 85/482 - (17%)

  Fly    73 YLLGSRNLKVFPVAMSLIASYIS-----GVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYI 132
            |.|..|::..:||..||.||.|.     |:...|..|.:...|.: |.....::|.|    ::::
  Rat    53 YFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFE-WNALFVVLLLG----WLFV 112

  Fly   133 PVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILF----LPFIVYVPAIALNQVSGINLHVI 193
            ||:....|.:..:||..||..  |.|..::.:|...|:    :...::..|:.:.|..|.|::..
  Rat   113 PVYLTAGVITMPQYLRKRFGG--RRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYAS 175

  Fly   194 AVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYA----NGLNVLFD------- 247
            .:.::.:.:.||..||:.|:::||..|..|    :||.|.:.|.||    .|.:.|||
  Rat   176 VIALLGITMIYTVTGGLAALMYTDTVQTFV----ILAGAFILTGYAFHEVGGYSGLFDKYLGAVT 236

  Fly   248 ------DAAKGGRLIFNNT--NPSPYVRHTV---------WSVLIGGFS-----YWTSFNAVNQT 290
                  |.|.|.   .::|  .|.|...|.:         |..|:.|.:     ||.|    :|.
  Rat   237 SLTVSKDPAVGN---ISSTCYQPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCS----DQV 294

  Fly   291 MVQRYMSLPSLKKARAS---------MAIFTIGVAAFVSVCCY---VGLLIYEMYKDCDPLSAGL 343
            :|||.::..:|...:|.         |.:|.:.:...:|...|   |..::.|:   |..:....
  Rat   295 IVQRCLAGKNLTHIKAGCILCGYLKLMPMFLMVMPGMISRILYPDEVACVVPEV---CKRVCGTE 356

  Fly   344 ITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSER 408
            :...:...|..||:.:.:  |:.||.:|.:..|.:|||:.:.||:|.:...||..   :::|...
  Rat   357 VGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYT---RLRPRAG 416

  Fly   409 ASTILVKSTVIVLGFVALSLVF--VLEQLSG--ILSICTSMTAIAAGTTFGLFTLGMLVPWANTV 469
            ...:|:...:.|:..||:|:.:  |::...|  :.....|:::..|.....:|.|.:.||..|..
  Rat   417 DRELLLVGRLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNEK 481

  Fly   470 GTAVGGIASALLAGWISFGTQFTIAAG 496
            | |..|:...||.|......:|....|
  Rat   482 G-AFWGLIGGLLMGLARLIPEFFFGTG 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	116/482 (24%)
Slc5a2	NP_072112.2	SLC5-6-like_sbd	22..670	CDD:444915	116/482 (24%)