Protein Alignment SLC5A11 and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Alignment Length: 558
• Identity: 115/558 - (20%)
• Similarity: 222/558 - (39%)
• Gaps: 99/558 - (17%)

  Fly    73 YLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIA-----IMLQGIAVSYVYI 132
            :.|...::..:|:..||.||.|.....:|........|     ||||     .:|..:.:.:|::
Mouse    58 FFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASG-----IAIAAVEWNALLMVLVLGWVFL 117

  Fly   133 PVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPF----IVYVPAIALNQVSGINLHVI 193
            |::....|.:..|||..||..  :.:..::.:|...:.:..    |::..||.:....|:||::.
Mouse   118 PIYIKAGVLTMPEYLRKRFGG--KRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLA 180

  Fly   194 AVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANG--------LNVLFDDAA 250
            ..:::.:..|||..||:.:|::||:.|..:|.|..|.:...|.....|        :|.: ....
Mouse   181 VFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAI-PSVV 244

  Fly   251 KGGRLIFNNT--NPSPYVRHTV---------WSVLIGGFS-----YWTSFNAVNQTMVQRYMSLP 299
            :|..|..:..  .|.|...|..         |..||.|.:     ||    ..:|.:|||.:...
Mouse   245 EGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYW----CADQVIVQRCLCGK 305

  Fly   300 SLKKARAS---------MAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFV 355
            ::...:|:         :.:|.:.:...:|...|...:...:..:|:......:...:...|..|
Mouse   306 NMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLV 370

  Fly   356 VQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIV 420
            ::.:..  |:.||.::.:..:.:|||:.:.||.|.:...|:... .:.:.|||  .:::...:..
Mouse   371 LELMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTK-IRKKASER--ELMIAGRIFG 430

  Fly   421 LGFVALSLVFV-LEQLS--GILSICTSMTAIAAGTTFG-LFTLGMLVPWANTVGTAVGGIASALL 481
            :..:|:|:::| |.|:|  |.|.......:...|...| :|.|.:.....|..| |..|:...|:
Mouse   431 MVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQG-AFWGLMVGLV 494

  Fly   482 AGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATV 546
            .|.|....:|....|..      |:...|              .::.......|..|....|:.:
Mouse   495 VGLIRLIAEFVYGTGSC------VAPSNC--------------PKIICGVHYMYFAIILFFVSII 539

  Fly   547 IVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFS 584
            :::|  ||.:|:|.           |.:|  |.:.|:|
Mouse   540 VILG--VSFLTEPI-----------PDVH--LYRLCWS 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	108/528 (20%)
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:444915	115/558 (21%)