Protein Alignment SLC5A11 and slc5a9

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001107077.1
• Gene: slc5a9 / 564815
• ZFINID: ZDB-GENE-080513-3
• Length: 657
• Species: Danio rerio
• Alignment Length: 614
• Identity: 139/614 - (22%)
• Similarity: 241/614 - (39%)
• Gaps: 129/614 - (21%)

  Fly     2 EAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFG 66
            |..||..:|     :.|.||.:...|...:.||:      |.::....
Zfish    16 EVPAKFTLE-----AADIAVVVVYFVFVLAVGIW------SSIRANRG----------------- 52

  Fly    67 SEKMSEYLLGSRNLKVFPVAMSLIASYI-SGVTI----LGTTSEIYNYGTQY---WFIAIAIMLQ 123
              .:..|.|..|::..:|:..||::|.: ||:.|    .|....:...|.::   |.:
Zfish    53 --TVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNAAWVL------- 108

  Fly   124 GIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILF----LPFIVYVPAIALNQ 184
             ||:.::::||:.:..|.:..|||..||..  :.|..:|.:|..||:    :...::..|:.:..
Zfish   109 -IALGWIFVPVYISAGVVTMPEYLRKRFGG--QRIRIYMSVLSLILYILTKISTDIFSGALFIQV 170

  Fly   185 VSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILA---TVYANGLNVLF 246
            ..|.:|::..|:::.|...||..||:.||::|||.|.::|.:....:..:|   ..:..||.|.:
Zfish   171 SLGWDLYLSTVILLAVTALYTIAGGLTAVIYTDALQTVIMVIGAFVLMFIAFDKVGWYEGLLVQY 235

  Fly   247 DDAAKGGRLIFNNTN------------PSPYVRHTVWSVLIGGFS-----YWTSFNAVNQTMVQR 294
            :.||..  |...||.            ..|......|..||.|.:     .|    ..:|.:|||
Zfish   236 EKAAPA--LTVPNTTCHLPRSDAFHIFRDPVTGDIPWPGLIFGLTVLATWVW----CTDQVIVQR 294

  Fly   295 YMSLPSLKKARASMAI---------FTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQL 350
            .:|..:|..|:|...:         |.:.:...:|...|...:......:|..:....:...:..
Zfish   295 SLSAKNLSHAKAGSVLGGYLKVFPMFFVVMPGMISRALYPDEVACVDPDECQKICGAKVGCSNIA 359

  Fly   351 LPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVK 415
            .|..||:.:.  .||.||.||.:..|.:|||:.:.||:|.:...||.:   :::|......::|.
Zfish   360 YPKLVVELMP--VGMRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWQ---RIRPRASEKELMVV 419

  Fly   416 STVIVLGFVALSLVFV-------LEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPW--ANTVGT 471
            ..|.:|..||||:|::       ..||...:...||..:....|.|     .|.:.|  .|..|
Zfish   420 GRVFILLLVALSIVWIPVIQTANSGQLFDYIQAITSFLSPPITTVF-----IMAIFWGRVNEQG- 478

  Fly   472 AVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYH 536
            |..|:...|:.|.:....:|.            .....| |...||.::..|         :.|.
Zfish   479 AFWGLMVGLVVGMVRMIMEFV------------YGTPSC-GETDLRPSLLKD---------VHYL 521

  Fly   537 WINPIGVATVIVVGALVSLVTKPTNMKTL 565
            :...|.:|..:::...|||.|.|...|.|
Zfish   522 YFALILLALTVLIITAVSLCTAPIPEKHL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	130/588 (22%)
slc5a9	NP_001107077.1	SLC5sbd_SGLT4	42..657	CDD:271380	131/583 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750