Protein Alignment SLC5A11 and slc5a6a

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001020700.2
• Gene: slc5a6a / 563356
• ZFINID: ZDB-GENE-041001-177
• Length: 625
• Species: Danio rerio
• Alignment Length: 587
• Identity: 195/587 - (33%)
• Similarity: 310/587 - (52%)
• Gaps: 58/587 - (9%)

  Fly    14 FGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMS-EYLLGS 77
            |.:|||.:|:.::|.|...|:|:.                         ...|.::.: |:||..
Zfish     9 FSTVDYVIFVVLLVASAGIGLYYA-------------------------FSGGRQRTTQEFLLAD 48

  Fly    78 RNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGS 142
            |:::..||::||:|::.|.|.|||..||||.|||||||:..:..|..:..::::||||..|::.|
Zfish    49 RSMRCLPVSLSLLATFQSAVAILGAPSEIYTYGTQYWFLGCSYFLGLLIPAHIFIPVFYRLRLSS 113

  Fly   143 SYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFV 207
            :|||||:||...||...:..||...::::..::|.||:|||.|:|.:|....:.:.:||..||.:
Zfish   114 AYEYLELRFSKSVRICGTVTFIFQMVIYMGVVLYAPALALNAVTGFDLWGAVLAMGLVCTLYTAL 178

  Fly   208 GGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWS 272
            ||:|||:.||.:|.:|||...|||.::.|..|.|:..::..|..|.|:...:.||.|..|||.|:
Zfish   179 GGLKAVIWTDVFQTIVMFAGQLAVIVVGTHQAGGIAEVWRKAQNGSRIAGLDLNPDPLERHTFWT 243

  Fly   273 VLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARAS--------MAIFTIGVAAFVSVCCYVGLLI 329
            :.:||.....:...|||..||||:|..:.|:|..|        ..:.|:|        |.:||::
Zfish   244 LGVGGVFLMLALYGVNQAQVQRYLSSRTEKEAIMSCYAVFPCQQVVLTLG--------CLMGLVM 300

  Fly   330 YEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILE 394
            |..|.:..||..|.:|.:||::...|:..:..:.|:.|||:|.:|..|||::|...||.:.|.:|
Zfish   301 YARYGEESPLDQGYVTTNDQMVLYLVMDVLRDLPGLPGLFVACLFSGALSTISSAFNSLATVTME 365

  Fly   395 DIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTL 459
            |:::.........|| |:|.|...:..|.|.|::.::...:..:|....|:..:..|...|||.|
Zfish   366 DLIKPHVPAMTEARA-TLLSKMLALAYGLVCLAMAYIASLMGSVLQAALSIFGMVGGPLLGLFCL 429

  Fly   460 GMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPV---SVEGCVGNVTLRENIW 521
            ||..||||:.|..||..:..::|.||..|:    ....::...|||   ::...|||:|......
Zfish   430 GMFFPWANSTGALVGLASGLVMAFWIGIGS----FVSRMSLSALPVINATIIPDVGNMTTAVMTT 490

  Fly   522 VDEEQVFP-----LYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHR---FL 578
            :...:..|     ||.|||.|.:....|||:|||.:||.:|.|...|.|:|..:.||:..   ||
Zfish   491 LTTTKPRPSGVQALYSLSYMWYSAHNSATVVVVGLVVSFLTGPWKEKDLNPGTVYPVLGNLLFFL 555

  Fly   579 PK 580
            |:
Zfish   556 PQ 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	184/555 (33%)
slc5a6a	NP_001020700.2	SLC5-6-like_sbd	9..532	CDD:444915	185/560 (33%)