Protein Alignment SLC5A11 and slc5a5

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001082860.1
• Gene: slc5a5 / 561445
• ZFINID: ZDB-GENE-060503-585
• Length: 601
• Species: Danio rerio
• Alignment Length: 606
• Identity: 178/606 - (29%)
• Similarity: 293/606 - (48%)
• Gaps: 67/606 - (11%)

  Fly    14 FGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSR 78
            |..||||||..|:.:|...|: |..::|               ||       |..|:..:..|.|
Zfish    11 FCLVDYAVFAAMLGVSVGIGL-FQSLRK---------------TP-------GRSKVDSFFTGGR 52

  Fly    79 NLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSS 143
            .....||.:||.||::|.|.:||..||.|.||.::.::.:...|..:..:.:::|||..|::.||
Zfish    53 GFSAVPVGLSLCASFMSAVQVLGVPSETYLYGFKFLYMCLGQGLNSLMTAVLFVPVFYRLKITSS 117

  Fly   144 YEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVG 208
            .:||.|||...::.:.|..||:..:|:...:::.||:.|||.:|:|:........::|.|||.||
Zfish   118 SQYLGMRFGRGMQLLGSLQFIVATLLYTGIVIFAPAVILNQATGLNMWASLFSTGLICTFYTTVG 182

  Fly   209 GIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSV 273
            |:|||:.||.:|::||....:||.|..|:.|.|...:.:.|..|.|:.||:....|..|::.||.
Zfish   183 GMKAVIWTDVFQIVVMLSGFIAVFIQGTILAGGPARVLEIANNGSRINFNDFAIDPQRRYSFWSF 247

  Fly   274 LIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDP 338
            .:||...|.|....||..||||:|..:.|:|:.::.:..:|:...||.....|::::.:|.:|||
Zfish   248 TVGGTMVWLSMYGANQAQVQRYISCRTEKQAQLALLVNQVGLCLIVSSAATCGIVMFALYSNCDP 312

  Fly   339 LSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKM 403
            |..|.|:..||.:|..|:....:..|..|||:|..:...||::|..:|:.:.|.:||:      |
Zfish   313 LKIGRISAPDQYMPYLVLDIFRNHPGFPGLFLACAYSGTLSTVSTSINAMAAVTMEDV------M 371

  Fly   404 QP-----SERASTILVKSTVIVLGFVALSLVFVLEQLS-GILSICTSMTAIAAGTTFGLFTLGML 462
            :|     |:|...:|.::..:..|...:::..:...|. |:|....::..:..|...|.|.|||.
Zfish   372 KPWLITISQRKQLMLSRALSLFYGLGCITMAALSSLLDWGVLQGSFTVMGVVNGPLLGAFALGMF 436

  Fly   463 VPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCV-GNVTLRENIWVDEEQ 526
            ||..|..|...|......|:.|::.|:.....:.::.. .||.|...|: .|.||.....|....
Zfish   437 VPATNKPGVFSGVAVGFCLSLWLAVGSTIYPPSPQIMG-VLPTSAGQCLTTNATLNTTASVLASS 500

  Fly   527 VFPL-------YRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDL--------------- 569
            | ||       |.:||.:...:..:.|::||.:||.:|.||...::.|.|
Zfish   501 V-PLDYSFQNIYSISYLYFGALSTSAVVLVGVVVSYITGPTKKDSISPGLLRWNLEQKPCDASCH 564

  Fly   570 -------ISPVIHRFLPKECF 583
                   ::|......|||.|
Zfish   565 ILNETITLNPTEILLTPKELF 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	167/552 (30%)
slc5a5	NP_001082860.1	SLC5-6-like_sbd	14..549	CDD:320982	171/565 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950