Protein Alignment SLC5A11 and Slc5a3

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_059087.2
• Gene: Slc5a3 / 53881
• MGIID: 1858226
• Length: 718
• Species: Mus musculus
• Alignment Length: 542
• Identity: 117/542 - (21%)
• Similarity: 209/542 - (38%)
• Gaps: 94/542 - (17%)

  Fly    70 MSEYLLGSRNLKVFPVAMSLIASYISGVTILGT--TSEIYNYGTQYWFIAIAIMLQGIAVSYVYI 132
            :|.|.|..|::....:..||..|.|.....:|.  :.....:....|.....::||  .:.:|:|
Mouse    36 VSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQ--LLGWVFI 98

  Fly   133 PVFSALQVGSSYEYLEMRF--HSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAV 195
            |::....|.:..|||..||  |.:....|:...:|.....|...:|..|:.:.:..|.||:|..:
Mouse    99 PIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVI 163

  Fly   196 VIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLI---- 256
            :::.:....|..||:.||::||..|.|:|.:..|.:.:::.|...|    |::..:...|.
Mouse   164 LLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGG----FEEVKRRYMLASPDV 224

  Fly   257 --------FNNTNP--------------SPYVRHTVWSVLIGGFS-----YWTSFNAVNQTMVQR 294
                    .:|||.              .|......|...|.|.:     ||    ..:|.:|||
Mouse   225 ASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWYW----CADQVIVQR 285

  Fly   295 YMSLPSLKKARAS---------MAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQL 350
            .::..::..|:.|         :.:|.|.|...:|...:...:.....:.|..:........:..
Mouse   286 VLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIA 350

  Fly   351 LPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVK 415
            .|..|:..|.  .|:.||.:|.:..|.:|.|..:.||.|.:...|:.:   .::.|..:..:::.
Mouse   351 YPRLVMTLVP--VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYK---LIRKSASSRELMIV 410

  Fly   416 STVIVLGFVALSLVFV---LEQLSG-----ILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTA 472
            ..:.|...|.:|:.:|   :|...|     |..:...:|...|    .||.|.:.....|..|..
Mouse   411 GRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVA----ALFLLAIFWKRCNEQGAF 471

  Fly   473 VGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHW 537
            .||:|..:| |.:.....||..|.|.:.   |.:..|.:.::.            :.....:..|
Mouse   472 YGGMAGFVL-GAVRLILAFTYRAPECDQ---PDNRPGFIKDIH------------YMYVATALFW 520

  Fly   538 INPIGVATVIVVGALVSLVTKP 559
            |.  |:.|||     |||:|.|
Mouse   521 IT--GLITVI-----VSLLTPP 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	114/537 (21%)
Slc5a3	NP_059087.2	SLC5sbd_SMIT	9..718	CDD:271382	117/542 (22%)