Protein Alignment SLC5A11 and slc5a11

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001007301.1
• Gene: slc5a11 / 492334
• ZFINID: ZDB-GENE-041114-9
• Length: 668
• Species: Danio rerio
• Alignment Length: 472
• Identity: 113/472 - (23%)
• Similarity: 193/472 - (40%)
• Gaps: 108/472 - (22%)

  Fly    73 YLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAI----MLQGIAVSYVYIP 133
            |.|..:|:..:||..||.||.:.....:|....    |......|:|.    ||..:.:.::::|
Zfish    58 YFLAGKNMTWWPVGASLFASNVGSGHFIGLAGS----GAAAGIGAVAYEWNGMLMVLVMGWLFLP 118

  Fly   134 VFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFI------VYVPAIALNQVSGINLHV 192
            ::.|.:|.:..|||:.||..  :.|..|:.:|  .||:...      :|..|:.:.|....|:::
Zfish   119 IYIASRVTTMPEYLKKRFGG--KRIQLFLCVL--YLFIYIFTKISVDMYAGAVFIQQALQWNIYL 179

  Fly   193 IAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFD---DAAKGGR 254
            ..|:::.:...||..||:.||::|||.|.::|.:..|.:...:.....|...:.|   .|....|
Zfish   180 AVVLLLGITALYTIAGGLAAVIYTDAVQTIIMVIGALILMGFSFAEVGGFEAVLDKYPQAIPSIR 244

  Fly   255 LIFNNTNPSP------YVRHTV-----WSVLIGGFS-----YWTSFNAVNQTMVQRYMSLPSLKK 303
             :.|.|...|      ..||.|     |..:|.|.|     ||.|    :|.:|||.::..::..
Zfish   245 -VPNTTCGIPRDDAFHIFRHPVTSDLPWPGVILGMSIPSMWYWCS----DQVIVQRSLAAKNILH 304

  Fly   304 ARASMAIFTIGVAAFVSVCCYV-----GLLIYEMYKD---------CDPLSAGLITHDD------ 348
            |:....:     ||::.|..:.     |::...:|.|         |..:....:...|
Zfish   305 AKGGSLL-----AAYIKVLPFFMMVIPGMISRILYPDEVGCGDPEVCKEVCGNSVGCSDIAYAKL 364

  Fly   349 --QLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERAST 411
              :|||.          |:.||.:|.:..|.:|||:.:.||:|.:...|:.|   .::.:.....
Zfish   365 VMELLPA----------GLRGLMMAVMLAALMSSLTSIFNSSSTIFTMDLWR---NIRHTASEWE 416

  Fly   412 ILVKSTVIVLGFVALSLVFV-LEQLS--GILSICTS---------MTAIAAGTTF-------GLF 457
            :::...|.||..|.:|:::: |.|.|  |.|.|...         :|.|.....|       |.|
Zfish   417 LMIVGRVFVLVLVVVSVLWIPLVQASQGGQLFIYIQSISMYLQPPITVIFVAGCFWKRTNEKGAF 481

  Fly   458 TLGMLVPWANTVGTAVG 474
                   |...||.|||
Zfish   482 -------WGLMVGMAVG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	113/472 (24%)
slc5a11	NP_001007301.1	SLC5sbd_SGLT6	28..668	CDD:271381	113/472 (24%)