Protein Alignment SLC5A11 and ChT

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 124/578 - (21%)
• Similarity: 222/578 - (38%)
• Gaps: 139/578 - (24%)

  Fly    15 GSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRN 79
            |.|...:|..:|::   .||:.|                       ||...|::...|.:|..|:
  Fly     6 GVVSIVLFYLLILV---VGIWAG-----------------------RKKQSGNDSEEEVMLAGRS 44

  Fly    80 LKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSY 144
            :.:|....::.|:::.|..|.||...||..|. .|..|..    |.|:|.|:..:|.|
  Fly    45 IGLFVGIFTMTATWVGGGYINGTAEAIYTSGL-VWCQAPF----GYALSLVFGGIFFA------- 97

  Fly   145 EYLEMRFHSVVRSI----ASFMFILDEILFLPFI---VYVPAIALNQVSGINLHVI------AVV 196
              ..||....:..:    .||...:..:||||.:   |:..|..|..: |..|.||      ..|
  Fly    98 --NPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGEVFWAAGILAAL-GATLSVIIDMDHRTSV 159

  Fly   197 IVVVC--VFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILA--TVYANGLNVLFDDAAKGGRLIF 257
            |:..|  :|||..||:.:|.:||..|:..:|:.:......|  ..:...|:.|..|       ..
  Fly   160 ILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVD-------WI 217

  Fly   258 NNTNPSPYVRHTVWSVLI--GGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVS 320
            .:..|..:..:..:.:|:  ||..:        |...||.:|..:..:|:....:...|......
  Fly   218 GHVEPKKHWLYIDYGLLLVFGGIPW--------QVYFQRVLSSKTAGRAQLLSYVAAAGCILMAI 274

  Fly   321 VCCYVGLLIYEM------YKDCDPLSAGLITHDDQLLPL---FVVQSVGHIYGMSGLFIAGIFGA 376
            ....:|.:....      ||...||:   :.....:||:   ::.......:|: |...|.:..:
  Fly   275 PPVLIGAIAKATPWNETDYKGPYPLT---VDETSMILPMVLQYLTPDFVSFFGL-GAVSAAVMSS 335

  Fly   377 ALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSI 441
            |.||   ||::.|: ...::.:..|:.:.||.....:::..:||:|.:|..:...:..:.|:.|:
  Fly   336 ADSS---VLSAASM-FARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWSM 396

  Fly   442 CTSMTAIAAGTTFGLF-TLGMLVPW---ANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQK 502
            |:.:..:.      || .|.|:|.:   .||.|:....|.:  ||..:|.|
  Fly   397 CSDLVYVI------LFPQLLMVVHFKKHCNTYGSLSAYIVA--LAIRLSGG-------------- 439

  Fly   503 LPVSVEGCVGNVTLRENIWVDE---EQVFPLYRLSYHWINPIGVATVIVVGALVSLVT 557
                 |..:|...|.:....||   ||:||.             .|:.::.:||:|::
  Fly   440 -----EAILGLAPLIKYPGYDEETKEQMFPF-------------RTMAMLLSLVTLIS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	122/573 (21%)
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	123/577 (21%)