Protein Alignment SLC5A11 and slc5a8

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001351880.1
• Gene: slc5a8 / 394505
• XenbaseID: XB-GENE-479634
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 559
• Identity: 178/559 - (31%)
• Similarity: 302/559 - (54%)
• Gaps: 50/559 - (8%)

  Fly    18 DYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMS-EYLLGSRNLK 81
            ||.||..|:::|...|||:....                         |.:|.| ::|:|.|::.
 Frog    14 DYVVFALMLLISAVIGIYYAFAG-------------------------GGQKTSKDFLMGGRSMT 53

  Fly    82 VFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEY 146
            ..|||:||.||::|.||:|||.:|:|.:|:.:...|....:..:..|.|::|||..|.:.|:|||
 Frog    54 AVPVALSLTASFMSAVTVLGTPAEVYRFGSMFSIFAFTYAIVVVISSEVFLPVFYRLGITSTYEY 118

  Fly   147 LEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIK 211
            ||:||:..||.:.:.:||:..:|:...::|.||:|||||:|.:|....|...|||.||..:||:|
 Frog   119 LELRFNKFVRLLGTILFIIQTVLYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTMGGLK 183

  Fly   212 AVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIG 276
            |||.||.:||.:|.....:|.|.|.|...|:..:.:|:..|.||.|.:..|:|..||:.|::::|
 Frog   184 AVVWTDVFQVGIMVAGFSSVIIRAVVVQGGIGPILNDSYYGDRLNFWDFTPNPLQRHSFWTIVVG 248

  Fly   277 GFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSA 341
            |...||....|||:.||||::..:..:|:.|:.|..:|:.|.::.....||.:|.:||||||.:|
 Frog   249 GTFTWTGIYGVNQSQVQRYIACKTRFQAKLSLYINLLGLWAILACAVLSGLAMYSIYKDCDPWTA 313

  Fly   342 GLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPS 406
            ..::..|||:|...:..:....|:.|||::..:...||::|..:|:.:.|.:||:::..|: ..|
 Frog   314 QFVSAPDQLMPYLSLDILRDYPGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYFR-SLS 377

  Fly   407 ERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGT 471
            |...:.:.|.|.::.|.:.:::..:...:.|:|....|:..:..|...|||.||::.|:.|::|.
 Frog   378 ETKMSWISKGTSLIYGAICIAMAGLASLMGGLLQAALSIFGMVGGPLLGLFALGIIFPFVNSLGA 442

  Fly   472 AVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPL------ 530
            .:|.::...::.|:..|:|........:..| |:|:|||  |.|..|:.|.  ..|.|:
 Frog   443 VIGLLSGFAISLWVGIGSQIYPPTASSSLPK-PLSLEGC--NFTSFESNWT--TTVMPMMTTLIP 502

  Fly   531 ------------YRLSYHWINPIGVATVIVVGALVSLVT 557
                        |.|||.:.:.:|....:|||.:.||::
 Frog   503 EVSSRPELADSWYSLSYLYFSTLGTIVAVVVGVIASLLS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	177/556 (32%)
slc5a8	NP_001351880.1	SLC5sbd_SMCT1	7..547	CDD:271402	178/559 (32%)