Protein Alignment SLC5A11 and slc5a12

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_956662.1
• Gene: slc5a12 / 393339
• ZFINID: ZDB-GENE-040426-1343
• Length: 623
• Species: Danio rerio
• Alignment Length: 602
• Identity: 193/602 - (32%)
• Similarity: 314/602 - (52%)
• Gaps: 67/602 - (11%)

  Fly     1 MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDF 65
            ||.|.       ||.:.||.||..:.|:|:..|::|...:::|             .|.:
Zfish     1 METVG-------RFQAGDYVVFACLFVVSSGIGVFFAIKERNK-------------APSK----- 40

  Fly    66 GSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYV 130
                  |:|:|.|.:...|||:||.||::|.||::|..:::|.:|..|....:|........:.:
Zfish    41 ------EFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGASYVIFGVAYTFVVFFTAEL 99

  Fly   131 YIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAV 195
            ::|||....:.|:|||||:||..:||..|:.::|:..||:...:||.||:|||||:|.:|.....
Zfish   100 FLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIF 164

  Fly   196 VIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNT 260
            ...:||.||..:||:||||.|||:|::||.:..|.|.|..:..|.|:..::..:..||||...:.
Zfish   165 ATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSRAGGIENVWSTSRTGGRLQVFDF 229

  Fly   261 NPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYV 325
            :.||..|||.|::.:||...|.....|||:.:||.:|..:...||.::.:..:|:  ::.:.|.|
Zfish   230 DVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGL--WIILFCAV 292

  Fly   326 --GLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNST 388
              ||::|..|..|||.|:|||:..|||:|.||::.:|...|:.|||:|..|...||:::..:|:.
Zfish   293 VSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINAL 357

  Fly   389 SLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTT 453
            :.|:.||.|..||. ..|.||::.:.|:..:..|....::......:.||:....|:..:..|..
Zfish   358 ATVMYEDFVSQCFP-DLSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPV 421

  Fly   454 FGLFTLGMLVPWANTVGTAVGG-IASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVT-- 515
            .|||:||:|.|:.|..| |||| |....|:.|:..|. |...|...|:..|.::..||  |:|
Zfish   422 LGLFSLGILFPFTNLKG-AVGGLIVGISLSFWVGVGA-FIYPAPSNNTHALELNTAGC--NITAA 482

  Fly   516 ------------LRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPD 568
                        ..:..|:.:.    .|.:||.:.:.:|....:..|.|::|:|.|     :||.
Zfish   483 AFEPTSATVTQLTSDRNWLADS----WYSMSYLYYSAVGFIGTVAAGLLITLLTGP-----MDPK 538

  Fly   569 LISPVIHRFLPKE--CF 583
            |:.|.:.|.: ||  ||
Zfish   539 LLKPGMTRSV-KEVMCF 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	176/555 (32%)
slc5a12	NP_956662.1	SLC5sbd_SMCT2	4..533	CDD:212089	180/570 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950