Protein Alignment SLC5A11 and RGD1563815

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_006256382.1
• Gene: RGD1563815 / 365549
• RGDID: 1563815
• Length: 695
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 117/593 - (19%)
• Similarity: 224/593 - (37%)
• Gaps: 145/593 - (24%)

  Fly    63 HDFGSEKMSEYLLGSRNLKVFPVAMSLIAS-----YISGVTILGTTSEIYNYGTQYWFIAIAIML 122
            |..|:.|  ::.|..:||..:.:.:|:.:|     :..|:..:|..|.| ..|...|.....:.:
  Rat    48 HSRGTIK--DFFLAGQNLAWWLMGLSIYSSTVGSGHFMGLAGIGAASGI-AVGAFEWNTVFMLFM 109

  Fly   123 QGIAVSYVYIPVFSALQVGSSYEYLEMRFHSV-VRSIASFMFILDEILF-LPFIVYVPAIALNQV 185
            .|    ::::|::|...|.:..|||:.||.|| ::...||:|::..||. :...:...|:.|..|
  Rat   110 LG----WIFVPIYSKAGVVTLPEYLKKRFGSVRIQLFFSFVFLIVYILSRISMEIGFGAMFLKMV 170

  Fly   186 SGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAA 250
            ..|:::...:.::.:...||..||:..|.:.:..|..:|.|....:...|.....|...|.:..:
  Rat   171 WDIDIYQTMLTVLTITGVYTITGGLATVAYVETLQAGIMVLGSALLMGYAFYEVGGYQELVNKYS 235

  Fly   251 KGGRLIFNNTN----PSPYV---------RHTV-----W-SVLIGGFSYWTSFNAVNQTMVQRYM 296
            |.........|    |..|.         |..|     | .:::|..:....:...:|..|||::
  Rat   236 KAIPSTIQQGNWTAKPECYTPREDAFHVFRSCVSGDVPWPGLVLGATTVSLFYGCADQVSVQRFL 300

  Fly   297 SLPSLKKARASM-------------AIFTIGVAAFVS-------VCCYVGLLIYEMYKDCDPL-- 339
            :    .|:|..|             .:|.:.:...:|       |.|.|.       .:|:..
  Rat   301 A----GKSRLHMEGGCLLCGYLKLLPMFLMVMPGMISRVLFPDQVACVVP-------SECEKFCG 354

  Fly   340 -SAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKM 403
             ..|.......:|.|.|:.|     |:.|..::.:..:.:|||:.:.||:|.:...:|...   :
  Rat   355 RGTGCSALAYPVLVLGVMPS-----GLQGFMLSTVCASLMSSLTSIFNSSSALFTLNIYTW---I 411

  Fly   404 QPSERASTILVKSTVIVLGFVALSLVFV----------LEQLSGILSIC--TSMTAIAAGTTF-- 454
            :|:.....:::.....|:..:|:::|::          |.:...||..|  .|:||:.....|
  Rat   412 RPTATEKELMIAGRFFVIILLAVTIVWIPIIEMAPSETLFEYMQILKSCLTPSVTAVFLLAVFCK 476

  Fly   455 -----GLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNV 514
                 |.|       |...:|:.:|  ...|||.:. :|..   ..||  .::.|:.:.|
  Rat   477 RVNEQGAF-------WGLILGSTIG--VFRLLAEFF-YGPP---TCGE--DRQCPIFICG----- 521

  Fly   515 TLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLP 579
                              |.|.:.....:...|::...:||.|:|         :....:|..
  Rat   522 ------------------LHYLYFGFCLLLVSILIILAISLATEP---------IADDHLHGL-- 557

  Fly   580 KECFSGRN 587
              |:|.||
  Rat   558 --CWSLRN 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	109/560 (19%)
RGD1563815	XP_006256382.1	SLC5-6-like_sbd	26..695	CDD:294310	117/593 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840