Protein Alignment SLC5A11 and Slc5a6

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_808538.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 595
• Identity: 194/595 - (32%)
• Similarity: 299/595 - (50%)
• Gaps: 68/595 - (11%)

  Fly    14 FGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSR 78
            |..|||.||..::|||...|:|..|                        ..:|...:.|.|:..|
Mouse    23 FSVVDYVVFGLLLVLSLVIGLYHAC------------------------RGWGHHTVGELLMADR 63

  Fly    79 NLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSS 143
            .:...|||:||:|::.|.|.|||..:||:.:||||||:..:..|..:..::::||||..|.:.|:
Mouse    64 KMGCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSA 128

  Fly   144 YEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVG 208
            |||||:||:..||...:..||...::::...:|.|::|||.|:|.:|.:..:.:.:||..||.:|
Mouse   129 YEYLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALG 193

  Fly   209 GIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSV 273
            |:|||:.||.:|.|||||..|.|.|:......||..:::..::.|.:...|.:|.|:||||.|::
Mouse   194 GLKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINLDPDPFVRHTFWTL 258

  Fly   274 LIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVC--CYVGLLI---YEMY 333
            ..||.....|...|||..||||:|  |..:..|.::.:.:.....|::|  |.:||::   |.||
Mouse   259 AFGGVFMMLSLYGVNQAQVQRYLS--SHSERAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYNMY 321

  Fly   334 KDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVR 398
            .....|....   .|||:..||:..:..:.|:.|||:|.:|..:||::|...||.:.|.:||:::
Mouse   322 SMSPELKQAA---PDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQ 383

  Fly   399 GCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLV 463
            ..|. |.:|..:.:|.:......|.|.|.:.::...|..:|....|:..:..|...|||.||:..
Mouse   384 PWFP-QLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCLGLFF 447

  Fly   464 PWANTVGTAVGGIASALLAGWISFGT-----QFTIAAGELN--SQKLPVSVEGCVGNVTLRENIW 521
            |.||.:|..||.:....:|.||..|:     ...:|...||  |..||.:|  .|..||
Mouse   448 PCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAVAPPPLNGSSSFLPANV--TVAAVT------ 504

  Fly   522 VDEEQVFP-----------LYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIH 575
                .|.|           .|.|||.|.:.....||||||.:|||:|.....::|:|..|.||:.
Mouse   505 ----TVMPSTLSKPTGLQHFYSLSYLWYSAHNSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLP 565

  Fly   576 R---FLPKEC 582
            :   .||..|
Mouse   566 KLLALLPLSC 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	183/561 (33%)
Slc5a6	NP_808538.1	SLC5-6-like_sbd	23..548	CDD:444915	185/566 (33%)