Protein Alignment SLC5A11 and Slc5a10

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001100477.1
• Gene: Slc5a10 / 303205
• RGDID: 1305232
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 130/587 - (22%)
• Similarity: 236/587 - (40%)
• Gaps: 167/587 - (28%)

  Fly    70 MSEYLLGSRNLKVFPVAMSLIAS------YI--------SGVTILGTTSEIYNYGTQYWFIAIAI 120
            :|.|.|..|::..:|:..||.||      :|        .|:.:.|     :.:...|..:|:|
  Rat    47 VSGYFLAGRDMAWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAG-----FEWNATYVLLALA- 105

  Fly   121 MLQGIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILF----LPFIVYVPAIA 181
                    :|::|::.:.::.:..||::.||..  :.|..::.:|..:|.    :...:|..|:.
  Rat   106 --------WVFVPIYVSSEIVTLPEYIQKRFGG--QRIRMYLSVLSLLLSVFTKISIDLYAGALF 160

  Fly   182 LNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLF 246
            ::...|.|.::..::.:.:...||..||:..|::|||.|..:|.:..:.:|:.|.....|...|
  Rat   161 VHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTAIMVVGAVILAVKAFNQIGGYEQL- 224

  Fly   247 DDAAKGGRLIFNNTNPSPYVRHTV---------------------WSVLIGGFS-----YWTSFN 285
             :||      :....||..:.:|.                     |:.:..|.:     ||
  Rat   225 -EAA------YAQATPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYW---- 278

  Fly   286 AVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITH---- 346
            ..:|.:|||.:|..:|..|:|...:     |:::.: ..:||:|          ..|:|:.
  Rat   279 CTDQVIVQRSLSARNLNHAKAGSIL-----ASYLKM-LPMGLMI----------MPGMISRVLFP 327

  Fly   347 DD-----------------------------QLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLS 382
            ||                             :|:|:          |:.||.||.:..|.||||:
  Rat   328 DDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPI----------GLRGLMIAVMMAALLSSLT 382

  Fly   383 VVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLE-QLSGILSI-CTSM 445
            .:.||:|.:...||.|. |:....||...::.:..::||..|:::.:.||: ..||.|.| ..|:
  Rat   383 SIFNSSSTLFTMDIWRQ-FRPGAGERELLLVGRLVIVVLVGVSVAWIPVLQGSNSGQLFIYMQSV 446

  Fly   446 TAIAAGTTFGLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGC 510
            |:..|.....:|.||:....||..| |..|:.:.||.|.:....:|             :..|..
  Rat   447 TSSLAPPVTAIFLLGIFWRRANEQG-AFWGLMAGLLVGALRLVLEF-------------LYPEPH 497

  Fly   511 VGNVTLRENIWVDEEQVFPLYRLSY-HWINPIGVATVIVVGALVSLVTKPTNMK--------TLD 566
            .|.:..|.         |||..:.| |:...:...|..|:.| .||::.|...:        |||
  Rat   498 CGQIDTRP---------FPLGSIHYLHFAIALFFLTCAVMAA-GSLLSPPPQQRQIENLTWWTLD 552

  Fly   567 PD 568
            |:
  Rat   553 PN 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	124/565 (22%)
Slc5a10	NP_001100477.1	SLC5-6-like_sbd	17..596	CDD:444915	130/587 (22%)