Protein Alignment SLC5A11 and Slc5a11

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 112/531 - (21%)
• Similarity: 206/531 - (38%)
• Gaps: 99/531 - (18%)

  Fly     1 MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDF 65
            :||..:|.||     ..|..|.:...:...:.|::                  .|...||
  Rat    16 LEAFPQKSME-----PADIVVLVLYFLFVLAVGLW------------------STVRTKR----- 52

  Fly    66 GSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQG----IA 126
              :.:..|.|...::..:||..||.||.:.....:|....    |........|..|.|    :.
  Rat    53 --DTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGS----GAAVGISVAAYELNGLFSVLM 111

  Fly   127 VSYVYIPVFSALQVGSSYEYLEMRFHS-----VVRSIASFMFILDEILFLPFIVYVPAIALNQVS 186
            ::::::|::.|.||.:..|||..||..     .:..:..|::|..:|   ...:|..||.:.|..
  Rat   112 LAWIFLPIYIAGQVTTMPEYLRRRFGGSRIPITLAVLYLFIYIFTKI---SVDMYAGAIFIQQSL 173

  Fly   187 GINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDD--- 248
            .::|::..|.::.|...||..||:.||::|||.|.::|.:....:...:.....|:..|.|.
  Rat   174 HLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVIMLIGAFILMGYSFAAVGGMEGLKDQYFL 238

  Fly   249 AAKGGRL--------------IFNNTNPSPYVRHTVWSVLIGGFS-----YWTSFNAVNQTMVQR 294
            |....|.              ||.:    |......|..::.|.|     ||    ..:|.:|||
  Rat   239 ALASNRSENSSCGLPREDAFHIFRD----PLTSDLPWPGILFGMSIPSLWYW----CTDQVIVQR 295

  Fly   295 YMSLPSLKKARAS--MAIFTIGVAAFVSVCCYVGLLIYEMYKD---------CDPLSAGLITHDD 348
            .::..:|..|:..  ||.:...:..|:.|  :.|::...::.|         |..:.:......|
  Rat   296 SLAAKNLSHAKGGSLMAAYLKVLPLFLMV--FPGMVSRILFPDQVACAHPDICQRVCSNPSGCSD 358

  Fly   349 QLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTIL 413
            ...|..|::.:.  .|:.||.:|.:..|.:|||:.:.||.|.:...|:   ...::|......::
  Rat   359 IAYPKLVLELLP--TGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDL---WHHIRPRASERELM 418

  Fly   414 VKSTVIVLGFVALSLVFV----LEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVG 474
            :...|.||..|.:|::::    ..|...:.....|:::........:|.:|......|..| |..
  Rat   419 IVGRVFVLALVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKG-AFS 482

  Fly   475 GIASALLAGWI 485
            |:...||.|.:
  Rat   483 GLILGLLLGLV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	107/515 (21%)
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:444915	107/514 (21%)