Protein Alignment SLC5A11 and Slc5a2

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_573517.1
• Gene: Slc5a2 / 246787
• MGIID: 2181411
• Length: 670
• Species: Mus musculus
• Alignment Length: 588
• Identity: 135/588 - (22%)
• Similarity: 238/588 - (40%)
• Gaps: 130/588 - (22%)

  Fly    73 YLLGSRNLKVFPVAMSLIASYIS-----GVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYI 132
            |.|..|::..:||..||.||.|.     |:...|..|.:...|.: |.....::|.|    ::::
Mouse    53 YFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFE-WNALFVVLLLG----WLFV 112

  Fly   133 PVFSALQVGSSYEYLEMRF--HSV---VRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHV 192
            ||:....|.:..:||..||  |.:   :..::.|::|..:|   ...::..|:.:.|..|.|::.
Mouse   113 PVYLTAGVITMPQYLRKRFGGHRIRLYLSVLSLFLYIFTKI---SVDMFSGAVFIQQALGWNIYA 174

  Fly   193 IAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYA----NGLNVLFD------ 247
            ..:.::.:.:.||..||:.|:::||..|..|    :||.|.:.|.||    .|.:.|||
Mouse   175 SVIALLGITMIYTVTGGLAALMYTDTVQTFV----ILAGAFILTGYAFHEVGGYSGLFDKYLGAM 235

  Fly   248 -------DAAKGGRLIFNNT--NPSPYVRHTV---------WSVLIGGFS-----YWTSFNAVNQ 289
                   |.:.|.   .::|  .|.|...|.:         |..|:.|.:     ||.|    :|
Mouse   236 TSLTVSKDPSVGN---ISSTCYQPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCS----DQ 293

  Fly   290 TMVQRYMSLPSLKKARAS---------MAIFTIGVAAFVSVCCY---VGLLIYEMYKDCDPLSAG 342
            .:|||.::..:|...:|.         |.:|.:.:...:|...|   |..::.|:   |..:...
Mouse   294 VIVQRCLAGKNLTHIKAGCILCGYLKLMPMFLMVMPGMISRILYPDEVACVVPEV---CKRVCGT 355

  Fly   343 LITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSE 407
            .:...:...|..||:.:.:  |:.||.:|.:..|.:|||:.:.||:|.:...||..   :::|..
Mouse   356 EVGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYT---RLRPRA 415

  Fly   408 RASTILVKSTVIVLGFVALSLVF--VLEQLSG--ILSICTSMTAIAAGTTFGLFTLGMLVPWANT 468
            ....:|:...:.|:..||:|:.:  |::...|  :.....|:::..|.....:|.|.:.||..|.
Mouse   416 GDKELLLVGRLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNE 480

  Fly   469 VGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRL 533
            .| |..|:...||.|......:|...:|            .||            .....|....
Mouse   481 KG-AFWGLVGGLLMGLARLIPEFFFGSG------------SCV------------RPSACPALFC 520

  Fly   534 SYHWINPIGVATVIVVGAL---VSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGRNLHAQAHKN 595
            ..|::. ..:...|..|.|   :||.|.|...|.|         ||.:    ||.|  |::..:.
Mouse   521 RVHYLY-FAIILFICSGILTLGISLCTAPIPQKHL---------HRLV----FSLR--HSKEERE 569

  Fly   596 LLN 598
            .|:
Mouse   570 DLD 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	123/544 (23%)
Slc5a2	NP_573517.1	SLC5-6-like_sbd	22..670	CDD:294310	135/588 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750