Protein Alignment SLC5A11 and cho-1

DIOPT Version :9

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_502539.1
• Gene: cho-1 / 178274
• WormBaseID: WBGene00000501
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 623
• Identity: 130/623 - (20%)
• Similarity: 226/623 - (36%)
• Gaps: 133/623 - (21%)

  Fly    20 AVFLGMI------VLSTSTGIYFGCIKKSKVKLE-EAEPTLPTTTPKRRKHDFGSEKMSEYLLGS 77
            |..||::      ||....||:.|  :|||...| |:|....|               .|.:|..
 Worm     2 ADLLGIVAIVFFYVLILVVGIWAG--RKSKSSKELESEAGAAT---------------EEVMLAG 49

  Fly    78 RNLKVFPVAMSLIASYISGVTILGTTSEIYNYG-------TQYWFIAIAIMLQGIAVSYV----- 130
            ||:.......::.|:::.|..|.||...:||.|       ..|   ||::::.|:..:..
 Worm    50 RNIGTLVGIFTMTATWVGGAYINGTAEALYNGGLLGCQAPVGY---AISLVMGGLLFAKKMREEG 111

  Fly   131 YIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFI---LDEILFLPFIVYVPAIALNQVSGINLHV 192
            ||.:....|            |...:.|...|::   |.|..:...|:......|:.:.||:::.
 Worm   112 YITMLDPFQ------------HKYGQRIGGLMYVPALLGETFWTAAILSALGATLSVILGIDMNA 164

  Fly   193 IAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIF 257
            ...:...:.|||||.||..||.:||..|:..:|:.:......|.|:         |.||.   |.
 Worm   165 SVTLSACIAVFYTFTGGYYAVAYTDVVQLFCIFVGLWVCVPAAMVH---------DGAKD---IS 217

  Fly   258 NNTNPSPYVRHTVWSVLIGGF---SYWTS------FNAVN-QTMVQRYMSLPSLKKARASMAIFT 312
            .|...        |...||||   |.|..      |..:. |...||.:|..:...|:....:..
 Worm   218 RNAGD--------WIGEIGGFKETSLWIDCMLLLVFGGIPWQVYFQRVLSSKTAHGAQTLSFVAG 274

  Fly   313 IGVAAFVSVCCYVGLLI----YEMYKDCDPLSAGL----ITHD--DQLLPLFVVQSVGHIYGMSG 367
            :|..........:|.:.    :.| .|..|.:.|.    |..|  :.::||.............|
 Worm   275 VGCILMAIPPALIGAIARNTDWRM-TDYSPWNNGTKVESIPPDKRNMVVPLVFQYLTPRWVAFIG 338

  Fly   368 LFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVL 432
            |  ..:..|.:||....:.|.:.:...:|.:...:...||:...|:::..:|.:|.:|..:...:
 Worm   339 L--GAVSAAVMSSADSSVLSAASMFAHNIWKLTIRPHASEKEVIIVMRIAIICVGIMATIMALTI 401

  Fly   433 EQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVG---GIASALLAG--WISFGTQFT 492
            :.:.|:..:|..:..:   ..|......:.:|.:||.|:..|   |:...|:.|  .:|....|.
 Worm   402 QSIYGLWYLCADLVYV---ILFPQLLCVVYMPRSNTYGSLAGYAVGLVLRLIGGEPLVSLPAFFH 463

  Fly   493 IAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVT 557
            ........|..|......:.::.....:.:..|::|...|||..|         .|:|.:|::
 Worm   464 YPMYTDGVQYFPFRTTAMLSSMATIYIVSIQSEKLFKSGRLSPEW---------DVMGCVVNI-- 517

  Fly   558 KPTNMKTLDPDLISPVIHRFLPKE---CFSGRNLHAQA 592
                          |:.|..||.:   ..|...|:.:|
 Worm   518 --------------PIDHVPLPSDVSFAVSSETLNMKA 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	123/582 (21%)
cho-1	NP_502539.1	SLC5sbd_CHT	7..492	CDD:271368	111/542 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810