Protein Alignment SLC5A11 and Slc5a6

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_570102.1
• Gene: Slc5a6 / 170551
• RGDID: 69648
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 193/582 - (33%)
• Similarity: 298/582 - (51%)
• Gaps: 42/582 - (7%)

  Fly    14 FGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSR 78
            |..|||.||..::|||...|:|..|                        ..:|...:.|.|:..|
  Rat    23 FSVVDYVVFGLLLVLSLVIGLYHAC------------------------RGWGRHTVGELLMADR 63

  Fly    79 NLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSS 143
            .:...|||:||:|::.|.|.|||..:|||.:||||||:..:..|..:..::::||||..|.:.|:
  Rat    64 KMGCLPVALSLLATFQSAVAILGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSA 128

  Fly   144 YEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVG 208
            |||||:||:..||...:..||...::::...:|.|::|||.|:|.:|.:..:.:.:||..||.:|
  Rat   129 YEYLELRFNKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALG 193

  Fly   209 GIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSV 273
            |:|||:.||.:|.|:|||..|.|.|:......||..::..|::.|.:.....:|.|:||||.|::
  Rat   194 GLKAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRHTFWTL 258

  Fly   274 LIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVC--CYVGLLIYEMYKDC 336
            ..||.....|...|||..||||:|..|.|  .|.::.:.:.....|::|  |.:||:::..||..
  Rat   259 AFGGVFMMLSLYGVNQAQVQRYLSSHSEK--AAVLSCYAVFPCQQVALCMSCLIGLVMFAYYKKY 321

  Fly   337 DPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCF 401
            ...........|||:..||:..:..:.|:.|||:|.:|..:||::|...||.:.|.:||:::..|
  Rat   322 SMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQPWF 386

  Fly   402 KMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWA 466
            . |.:|..:.:|.:|.....|.|.|.:.:|...|..:|....|:..:..|...|||.|||..|.|
  Rat   387 P-QLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCLGMFFPCA 450

  Fly   467 NTVGTAVGGIASALLAGWISFGT-----QFTIAAGELN--SQKLPVSVEGCVGNV-TLRENIWVD 523
            |.:|..||.:....:|.||..|:     ....|:..||  |..||.::  .|..| ||..:....
  Rat   451 NPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAAASPPLNGSSSFLPSNL--TVATVTTLMPSTLSK 513

  Fly   524 EEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHR---FLPKEC 582
            ...:...|.|||.|.:.....|||.||.:|||:|.....::|:|..|.||:.:   .||..|
  Rat   514 PTGLQQFYSLSYLWYSAHNSTTVIAVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALLPLSC 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	182/548 (33%)
Slc5a6	NP_570102.1	SLC5-6-like_sbd	23..548	CDD:444915	184/553 (33%)