DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8460 and Chid1

DIOPT Version :9

Sequence 1:	NP_609190.2	Gene:	CG8460 / 34115	FlyBaseID:	FBgn0031996	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_001136153.2	Gene:	Chid1 / 68038	MGIID:	1915288	Length:	393	Species:	Mus musculus

Alignment Length:	409	Identity:	168/409 - (41%)
Similarity:	246/409 - (60%)	Gaps:	35/409 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLRVALLLLLLTTVRGTLA-PDSHKSKS-----KTKESALRGGPQDQDVFDLGLVSPEPLAKDIV 66
            ||.|..|.|:..:|..||: .|:.|:.|     ||:.|       |:.|.|.|||..:..|:|:|
Mouse     4 LLHVLWLALVCGSVHTTLSKSDAKKAASKMLLEKTQFS-------DKPVQDRGLVVTDIKAEDVV 61

  Fly    67 SNHRGYFKETGL-RRFNGTTLGYVTPWNSHGYDVAKIFAKKFDIISPVWLQIVKQG-DRYAVAGT 129
            ..||.|...... |.|.|..||||||||||||||||:|..||..|||||||:.::| :.:.:.|.
Mouse    62 LEHRSYCSSRARERNFAGEVLGYVTPWNSHGYDVAKVFGSKFTQISPVWLQLKRRGREMFEITGL 126

  Fly   130 HDIDAGWLTDVRRKGKQVHNQRTVKVFPRFIFDHFTDRDIKLLLSDAQERTKVNDVLIKCCKDNG 194
            ||:|.||:..|::..|      .|::.||.:|:.:|..|.:.:|....|..:::..:.:..|:..
Mouse   127 HDVDQGWMRAVKKHAK------GVRIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVAQVAKNQH 185

  Fly   195 FDGLVLEVWSQLAGRIDDKILYTLVLQMAKELQKQQLRLILVIPPF----RKETGHLFGEKHMDK 255
            |||.|:||||||..:....:::.|. .:|:.|.:.:|.:||||||.    ..:.| :|..|..::
Mouse   186 FDGFVVEVWSQLLSQKHVGLIHMLT-HLAEALHQARLLVILVIPPAVTPGTDQLG-MFTHKEFEQ 248

  Fly   256 LFKHIYAFSLMTYDFSSVQRPGANAPLYFVRKAVETIAPEGCADMTAKRAKILLGLNMYGNDY-- 318
            |...:..|||||||:|:.|:||.||||.::|..|:.:.|:     :..|:|||||||.||.||
Mouse   249 LAPILDGFSLMTYDYSTSQQPGPNAPLSWIRACVQVLDPK-----SQWRSKILLGLNFYGMDYAA 308

  Fly   319 TPDGGGPITFSQYLDLVRHVKKHLTYDERDVENFFEI-KNDDGRHIVFYPTLYSINERIKLAQEL 382
            :.|...|:..::|:..::..:..:.:|.:..|:|||. ||..|||:||||||.|:..|::||:||
Mouse   309 SKDAREPVIGARYVQTLKDHRPRVVWDSQAAEHFFEYKKNRGGRHVVFYPTLKSLQVRLELAREL 373

  Fly   383 GTGISIWELGQGLNYFYDL 401
            |.|:|||||||||:|||||
Mouse   374 GVGVSIWELGQGLDYFYDL 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8460	NP_609190.2	GH18_SI-CLP	81..402	CDD:119355	141/329 (43%)
CG8460	NP_609190.2	Glyco_18	86..393	CDD:214753	130/314 (41%)
Chid1	NP_001136153.2	GH18_SI-CLP	77..393	CDD:119355	141/329 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835166
Domainoid	1	1.000	244	1.000	Domainoid score	I2196
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12229
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2836
Isobase	1	0.950	-	0	Normalized mean entropy	S4727
OMA	1	1.010	-	-		QHG54390
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003978
OrthoInspector	1	1.000	-	-		oto91992
orthoMCL	1	0.900	-	-		OOG6_105228
Panther	1	1.100	-	-	LDO	PTHR46066
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3718
SonicParanoid	1	1.000	-	-		X2735
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.880