DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8460 and chid1

DIOPT Version :9

Sequence 1:	NP_609190.2	Gene:	CG8460 / 34115	FlyBaseID:	FBgn0031996	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_956351.1	Gene:	chid1 / 337225	ZFINID:	ZDB-GENE-030131-9169	Length:	391	Species:	Danio rerio

Alignment Length:	408	Identity:	171/408 - (41%)
Similarity:	239/408 - (58%)	Gaps:	25/408 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRAPDALLLRVALLLLLLTTVRGTLAPDSHKSKSKTKESALRGGPQDQDVFDLGLVSPEPLAKDI 65
            |||....|    |:.|||..||.||:....|..||.:|:  .....::...|.|||..:|..:||
Zfish     1 MRADWTFL----LVCLLLPVVRSTLSKTDAKKASKVQEA--ESSVAERPAQDRGLVVTDPQWRDI 59

  Fly    66 VSNHRGYFKE-TGLRRFNGTTLGYVTPWNSHGYDVAKIFAKKFDIISPVWLQIVKQG-DRYAVAG 128
            |...:.:..: ...|:|.|..|||:|||||||||:||:|..|...:||||||:.::| :.:.:.|
Zfish    60 VREEKRFCHQCINTRQFKGAVLGYITPWNSHGYDIAKLFGPKLTSVSPVWLQLRRRGPESFHITG 124

  Fly   129 THDIDAGWLTDVRRKGKQVHNQRTVKVFPRFIFDHFTDRDIKLLLSDAQERTKVNDVLIKCCKDN 193
            .||.|.||:..||:..|:      .|:.||.:||.::.:|...:|....|..::....::..|..
Zfish   125 LHDHDPGWVKAVRKANKK------NKILPRLLFDGWSYQDYVSVLDSEDEMEELGREALEVAKAE 183

  Fly   194 GFDGLVLEVWSQLAGRIDDKILYTLVLQMAKELQKQQLRLILVIPP-FRKETGH--LFGEKHMDK 255
            ||||..||:||||.|. ..|.|..||..:.:.|...:|..:||||| ....||.  :||....:|
Zfish   184 GFDGYTLELWSQLGGN-KRKELVHLVTHLCETLNAGKLTCVLVIPPSVAPGTGQPGMFGRDDFEK 247

  Fly   256 LFKHIYAFSLMTYDFSSVQRPGANAPLYFVRKAVETIAPEGCADMTAKRAKILLGLNMYGNDYTP 320
            |...:.||||||||:|...|||.:|||.:||:.|..:|||     ...|.|||||:||||.|::.
Zfish   248 LAPVVDAFSLMTYDYSGPGRPGPSAPLPWVRECVLQLAPE-----NQWRHKILLGVNMYGLDFSS 307

  Fly   321 DGGG-PITFSQYLDLVRHVKKHLTYDERDVENFFEIKNDDG-RHIVFYPTLYSINERIKLAQELG 383
            .||. |:..::.::|::.||..|.:||...|:||..|.::| :|:|:||||..:..||.||.|||
Zfish   308 HGGAEPLLGARCIELLKEVKPKLQWDENTGEHFFNYKRNNGVKHVVYYPTLKFLQLRISLAAELG 372

  Fly   384 TGISIWELGQGLNYFYDL 401
            ||||:|||||||:|||||
Zfish   373 TGISMWELGQGLDYFYDL 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8460	NP_609190.2	GH18_SI-CLP	81..402	CDD:119355	146/327 (45%)
CG8460	NP_609190.2	Glyco_18	86..393	CDD:214753	135/312 (43%)
chid1	NP_956351.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		4/20 (20%)
		GH18_SI-CLP	76..391	CDD:119355	146/327 (45%)
		Glyco_18	80..382	CDD:214753	135/313 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578371
Domainoid	1	1.000	180	1.000	Domainoid score	I3465
eggNOG	1	0.900	-	-		E1_KOG2091
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12229
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2827
OMA	1	1.010	-	-		QHG54390
OrthoDB	1	1.010	-	-		D1067925at2759
OrthoFinder	1	1.000	-	-		FOG0003978
OrthoInspector	1	1.000	-	-		oto38772
orthoMCL	1	0.900	-	-		OOG6_105228
Panther	1	1.100	-	-	LDO	PTHR46066
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3718
SonicParanoid	1	1.000	-	-		X2735
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	16	15.840