Protein Alignment CG8475 and Phka1

DIOPT Version :9

• Sequence 1: NP_001260230.1
• Gene: CG8475 / 34114
• FlyBaseID: FBgn0031995
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_072148.2
• Gene: Phka1 / 64561
• RGDID: 621522
• Length: 1241
• Species: Rattus norvegicus
• Alignment Length: 1251
• Identity: 378/1251 - (30%)
• Similarity: 589/1251 - (47%)
• Gaps: 261/1251 - (20%)

  Fly    50 QLDIYYGIVKRQLLRYQSPITGLFPVMSTDQVVGSVRDSVYCASAVWSLYQAYRR---IDDDRGK 111
            :||.|..:|.:.:|.:|:|:|||.|. |.|:....|||:||...|||.|..|||:   .|:|:.|
  Rat    10 RLDGYARLVHQTILCHQNPVTGLLPA-SYDEKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAK 73

  Fly   112 SYELGQSTVKCMRGILECWVKQASRVELFKQRQSNQHALHSKFQLHTGEKIYPDEFYNHLQIDCV 176
            :|||.||.||.|||:|.|.::|..:||.||..||.:.:||:|:...|...:..|:.:.|||:|..
  Rat    74 AYELEQSVVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDAT 138

  Fly   177 SLYLLFLVQMITSGLQIIYTHDEVAFVQNLVYYVERAYRTPDFGMWERGSKYNNGTPEIHASSIG 241
            |:|||||.||..|||.||::.|||.|:||||:|:|.||:|.|||:||||.|.|.|..|::|||:|
  Rat   139 SVYLLFLAQMTASGLHIIHSLDEVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNASSVG 203

  Fly   242 MAKSALEAINGCNLFGEKGASWSVVYVDIDAHNRNRSIFETMLPRESSSKGVDASLLLTLSFPAF 306
            |||:||||::..:|||.||...||::|..|.....:||..::|||.|:||.||||||..:|||||
  Rat   204 MAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQSILNSLLPRASTSKEVDASLLSVVSFPAF 268

  Fly   307 ASHEDRLVEQTKQNVVNRLRCKMGFKRFTRDGFLSKNEDKSRRYYHSGELKEFEGLECEWPLFFI 371
            |..:..|||.|||.::.:|:.:.|..||.|||:.:..||.:|.||...|||.||.:|||||||:.
  Rat   269 AVEDSHLVEITKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKLFENIECEWPLFWT 333

  Fly   372 AMIIDGVFKNNNEQIEEFQNDLRRCLRTDVNGDPVVTMYYA--PDG-DGSYM------RAPSQSL 427
            ..|:||:|..|.||::|::..|...|....||.|::...|:  ||. |..|.      |.|...|
  Rat   334 YFILDGIFSGNTEQVQEYREALDAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKL 398

  Fly   428 -FLWGQSFFIIAQLLTAGLLHINELDPIRRYLPSYNRPRRAGRYSAFQAKPGTGTATDLVVQIVL 491
             .:||||.:|:..|:..|.|...|:||:.|...:..:|                   |:|||:.:
  Rat   399 PHMWGQSLYILGNLMAEGFLAPGEIDPLNRRFSTVPKP-------------------DVVVQVSI 444

  Fly   492 IAESMRLQAMMATYGIQTQTPHEVEPVQIWSSTELIKVYQHLGVNNKVGLSGRPCRPVGSLGTSK 556
            :||:..::|::...||..:|..||.|:::..:..|..:|..||.|:::.|||||.|.:|.|||||
  Rat   445 LAETEEIKAILKDKGIDVETIAEVYPIRVQPARILSHIYSSLGCNSRMKLSGRPYRLMGVLGTSK 509

  Fly   557 VYRICGMTVLCYPLIFEVSDFYLYRDMALLIDDIKTELQFVGKYWRLSGRPTVCLLIREEHMRDP 621
            :|.|........|...:...|||..|..::::.::|:|.::...||::|:||:...|....:.:.
  Rat   510 LYDIRKTIFTFTPQFIDQQQFYLALDNQMIVEMLRTDLSYLCSRWRMTGQPTITFPISHTMLDED 574

  Fly   622 QFKEMLDLLAMLKK---GYCDGMKVRIGRLQNLISSSCIEHLDFMNQS----------------- 666
            .......:||.|:|   ||..|.:::.|:|...:::||..||.||:..
  Rat   575 GASLNSSILAALRKMQDGYFGGARIQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDEDYDDE 639

  Fly   667 ----------DLTDNENAFSQINHEYIGY---------------------------------QSL 688
                      |.|.|.....:: ..|:.:                                 .||
  Rat   640 LDSGNWMDSYDSTRNARCGDEV-ARYLDHLLAHTGPHPKLTPTSRKGGLDRFRAAVQTTCDLMSL 703

  Fly   689 TDVPKAL------TYVEEKI------SVAHFDTKPTP-------------------------DII 716
            ....|.|      .|:..|:      |:...|:..:|                         .::
  Rat   704 VAKAKELHIQNVHMYLPTKLFQPSRPSLNLLDSPESPQDSQVPSVRVEVHLPRDQSGEVDFQSLV 768

  Fly   717 NALRSTDSIYCLCQLWGIILNREGPH-----FEVNGLNVNTALTQLYHRAGSLRYWRAVRYCSSL 776
            :.|:.|.|:.....:..::...:||.     :|..|..|...|::||.:.|.:|:|..:||.|.:
  Rat   769 SQLKETSSLQEQADILYMLYTMKGPDWNTELYEEGGSTVRELLSELYVKVGEIRHWGLIRYISGI 833

  Fly   777 LHHIVDSISPFITTVLVNGKELTVGIIGQ-KETVFDKPMTPAEIQNVMYTSVQPYDVIQAVLQQE 840
            |...|:::....|.:|...|.||||:..: :|.....|: |.|....:.......|:..:.|.||
  Rat   834 LRKKVEALDEACTDLLSYQKHLTVGLPPEPREKTISAPL-PYEALTKLIDEASEGDMNISTLTQE 897

  Fly   841 VVLYCGRLIATNPSMFRGILKIRIGWVLEAMRI----YLQISGQQSID-VDNLSPFQVRILLQKV 900
            :::|....:.|.|.:|..:.::|||.:::.|..    .|:.|.:::.: :.||||..::.||..:
  Rat   898 IMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHHI 962

  Fly   901 LTVSEWAVE---------------------------EKLTTLQ---------------------- 916
            |:..|:.||                           |:...:|
  Rat   963 LSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSVSPESQTS 1027

  Fly   917 -----------------------------------------------RRQLEGCLCRVPKHFYNK 934
                                                           ||:|:|.|.|||..||.|
  Rat  1028 GGHPSSIDLMSPTFLSPAACISASSGSFPTVCEPQTSKDSRQGQWQRRRRLDGALNRVPIGFYQK 1092

  Fly   935 IWEILQRTPQGILTQGHHLPATPTLTNMSRGELTFNLLVEETLICIDRPERRQITVELLCIVATI 999
            :|:|||:. .|:..:|..||::.| ..|:.||:.|::.||..|..:.:||.||:.||.: :|.|:
  Rat  1093 VWKILQKC-HGLSVEGFVLPSSST-REMTPGEIKFSVHVESVLNRVPQPEYRQLLVEAI-LVLTM 1154

  Fly  1000 LNRNPELHFKQALDLDGILA-EAFAMYCKDNNIQHQPK--PEHEQTKNEDLKAFYSLPYSE---- 1057
            | .:.|:|     .:..|:| |.......|..:|.|..  .:......:......:|.|..
  Rat  1155 L-ADIEIH-----SIGSIIAVEKIVHIANDLFLQEQKTLGADDIMLAKDPASGICTLLYDSAPSG 1213

  Fly  1058 ---TTGYLARAAVNKV 1070
               |..||::||...|
  Rat  1214 RFGTMTYLSKAAATYV 1229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8475	NP_001260230.1	Glyco_hydro_15	49..>468	CDD:279112	197/430 (46%)
		Glyco_hydro_15	<739..866	CDD:279112	37/132 (28%)
Phka1	NP_072148.2	Glyco_hydro_15	8..>439	CDD:279112	198/448 (44%)
		Glyco_hydro_15	<806..923	CDD:279112	33/117 (28%)
		Calmodulin-binding. /evidence=ECO:0000255	811..841		11/29 (38%)
		Calmodulin-binding. /evidence=ECO:0000255	1064..1104		16/40 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3635
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D38956at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101837
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720