Protein Alignment CG8475 and phka1a

DIOPT Version :9

• Sequence 1: NP_001260230.1
• Gene: CG8475 / 34114
• FlyBaseID: FBgn0031995
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: XP_005166576.1
• Gene: phka1a / 572183
• ZFINID: ZDB-GENE-031118-56
• Length: 1232
• Species: Danio rerio
• Alignment Length: 1195
• Identity: 371/1195 - (31%)
• Similarity: 578/1195 - (48%)
• Gaps: 246/1195 - (20%)

  Fly    50 QLDIYYGIVKRQLLRYQSPITGLFPVMSTDQVVGSVRDSVYCASAVWSLYQAYRR---IDDDRGK 111
            :||.|..||.:.:||:|.|:|||.|. |.:|....|||:||...:||:|..|||:   .|:|:.|
Zfish    10 KLDNYARIVHQTILRHQDPVTGLLPA-SKEQPDAWVRDNVYSILSVWALSLAYRKNADRDEDKAK 73

  Fly   112 SYELGQSTVKCMRGILECWVKQASRVELFKQRQSNQHALHSKFQLHTGEKIYPDEFYNHLQIDCV 176
            :|||.||.||.|||:|:|.::|..:||.||..:|...:||:|:...|...:..|..:.|||:|..
Zfish    74 AYELEQSVVKLMRGVLQCIMRQLDKVEKFKYSKSALDSLHAKYNTRTCATVVGDREWGHLQLDAT 138

  Fly   177 SLYLLFLVQMITSGLQIIYTHDEVAFVQNLVYYVERAYRTPDFGMWERGSKYNNGTPEIHASSIG 241
            |||:|||.||..|||.|:||.|||..||||::|:|.||:..|:||||||.|.|.|.||::|||||
Zfish   139 SLYMLFLAQMTASGLHIVYTQDEVDVVQNLLFYIEAAYKVADYGMWERGDKTNQGIPELNASSIG 203

  Fly   242 MAKSALEAINGCNLFGEKGASWSVVYVDIDAHNRNRSIFETMLPRESSSKGVDASLLLTLSFPAF 306
            |||:||||::..||||.||...|||:|..|.....:||..:||||.|:||.|||.||..:|:|||
Zfish   204 MAKAALEALDDLNLFGAKGGPDSVVHVLADDIQHCQSILNSMLPRASTSKEVDAGLLSIISYPAF 268

  Fly   307 ASHEDRLVEQTKQNVVNRLRCKMGFKRFTRDGFLSKNEDKSRRYYHSGELKEFEGLECEWPLFFI 371
            |..:..||..||:.::::|:.:.|..||.|||..:..||.:|.||.|.|||.||.:|||||||:.
Zfish   269 AVEDMELVNITKEEIISKLQGRYGCCRFLRDGHKTPKEDPNRLYYESAELKLFENIECEWPLFWT 333

  Fly   372 AMIIDGVFKNNNEQIEEFQNDLRRCLRTDVNGDPVVTMYYA--PDG-DGSYM------RAP-SQS 426
            .:|:||:|.|:.||:||::..|...|....:|..::...|:  |:. |..|:      |.| .:.
Zfish   334 YLILDGIFINSPEQVEEYREALEGILIKQKDGIRLLPELYSVPPEKVDEEYVNPHTVERIPLGKC 398

  Fly   427 LFLWGQSFFIIAQLLTAGLLHINELDPIRRYLPSYNRPRRAGRYSAFQAKPGTGTATDLVVQIVL 491
            ...||||.:::..||..|.|...|:||:.|            |:||. .||      |:|||:.:
Zfish   399 PLKWGQSLYVLGNLLAEGFLAPGEIDPLNR------------RFSAI-PKP------DVVVQVSI 444

  Fly   492 IAESMRLQAMMATYGIQTQTPHEVEPVQIWSSTELIKVYQHLGVNNKVGLSGRPCRPVGSLGTSK 556
            :||:..::|::...||..:|..::.|:::..|..|..:|..||.|.::||:|||.|.:|.|||||
Zfish   445 LAENEDIKALLQKNGIDVETVADIHPIRVQPSRVLSHIYARLGRNERLGLTGRPYRRIGVLGTSK 509

  Fly   557 VYRICGMTVLCYPLIFEVSDFYLYRDMALLIDDIKTELQFVGKYWRLSGRPTVCL-----LIREE 616
            :|.|........|...:...|||..|..::::.::|:|.::...||::|||||..     ::..:
Zfish   510 LYIIRNTIFSFTPQFIDHQQFYLALDNKMIVEMLRTDLSYLSSRWRMTGRPTVTFPISQTMLNHD 574

  Fly   617 HM-RDPQFKEMLDLLAMLKK---GYCDGMKVRIGRLQNLISSSCIEHLDF--------------- 662
            |. .||.      :||.|||   ||..|.:|:.|:|...:::.|..||.|
Zfish   575 HTDLDPA------VLATLKKLQDGYFGGARVQTGKLSEFLTTCCCAHLSFLDSGKTRSNKGWDED 633

  Fly   663 --------------MNQSDLTDN-ENAFSQINHEYIGYQ---------SLTDVPKALTYVEEKIS 703
                          :|.||.:|: .....|:.|..:..|         .|:....|.|...|.:|
Zfish   634 DDVEDDYFRGAVHDLNFSDDSDDLAQYLDQLLHAAVPVQGLRVEAEAKGLSRFKAAATKTREMVS 698

  Fly   704 VAH-------------------------FDTKPTP-----------------------------D 714
            :.:                         .:.|..|                             .
Zfish   699 LVNKAKDLQIHNLHMYLPNKLFRSPQPALNLKDFPGLGTDHSSEVVVPSENNLPRDTHGAIDYSS 763

  Fly   715 IINALRSTDSIYCLCQLWGIILNREGPHFEV----NGLNVNTALTQLYHRAGSLRYWRAVRYCSS 775
            ::..|:.|.|::....:..|:...:|..::.    .|..|.:.|.:||.:||.||.|..:|..|.
Zfish   764 LVQVLKDTQSLHDQADILYILFKDKGMDWDTQLHGKGTTVKSLLVELYEKAGDLRCWDIIRMISG 828

  Fly   776 LLHHIVDSISPFITTVLVNGKELTVGIIGQ-KETVFDKPMTPAEIQNVMYTSVQPYDVIQAVLQQ 839
            :|...|:.:....:.:|.:.|.||||:..: :|.....|:.|.::. ::........:..|:|.|
Zfish   829 MLRKKVEELDWACSDLLAHQKHLTVGLPPEPREKTITAPLPPDQLA-LLIDQASENSITIAILTQ 892

  Fly   840 EVVLYCGRLIATNPSMFRGILKIRIGWVLEAMRI----YLQISGQQSID-VDNLSPFQVRILLQK 899
            |:::|...:|.|..|:|..:.::|||.:::.|..    .|..||:::.: :..|||.:::.||..
Zfish   893 EIIVYLAMIIRTQRSLFSEMFRLRIGLIIQVMATELAQSLNCSGEEATESLMKLSPSELKNLLHH 957

  Fly   900 VLTVSE----------------------------------------------------WAVEEKL 912
            :|:..|                                                    |:::.|.
Zfish   958 ILSGKEFGVQRSVRSVEPGVSPVISIHEVGNVGATKSERAGISKLKSDMKMLEELRFSWSIQSKT 1022

  Fly   913 TT---------------------------------------LQRRQLEGCLCRVPKHFYNKIWEI 938
            .:                                       |:||:|:|.|.|||..||.|:|:|
Zfish  1023 FSGQSFDAEPVELARSRMPSIDGFDSSVSVGVPRDSRQGQWLRRRRLDGALNRVPVGFYQKVWKI 1087

  Fly   939 LQRTPQGILTQGHHLPATPTLTNMSRGELTFNLLVEETLICIDRPERRQITVELLCIVATILNRN 1003
            ||:. .|:..:|..||:: |...|:.||:.|.:.||..|..:.:||.||:.||.: :|.|:|...
Zfish  1088 LQKC-HGLSIEGFVLPSS-TTREMTPGEIKFAVHVERVLNRVPQPEYRQLLVEGI-LVLTMLADV 1149

  Fly  1004 PELHFKQALDLDGILAEAFAMYCKD 1028
            ........:.::.|:..|..|:.||
Zfish  1150 DIQSIGSIIHIEKIVHIANDMFYKD 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8475	NP_001260230.1	Glyco_hydro_15	49..>468	CDD:279112	194/430 (45%)
		Glyco_hydro_15	<739..866	CDD:279112	35/131 (27%)
phka1a	XP_005166576.1	Glyco_hydro_15	8..>439	CDD:279112	200/448 (45%)
		Glyco_hydro_15	<802..919	CDD:279112	33/117 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3635
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D38956at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910